Spinocerebellar Ataxia 3 (DBCOND0070950)

Identifiers

Synonyms

Machado Joseph Disease / Machado-Joseph Disease / Machado Joseph Disease (SCA3) / Spinocerebellar Ataxias Type 3 / Machado-Joseph Disease Type 3 / Machado-Joseph Disease / Spinocerebellar Ataxia 3 / Spinocerebellar Ataxia Type 3 / Azorean disease (disorder)

Associated Data

Indicated Drugs and Targets

Not Available

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT01096082	Safety and Efficacy of Lithium Carbonate in Patients With Spinocerebellar Ataxia Type 3	Lithium carbonate	treatment	2 / 3	completed
NCT04714307	Neuropsychiatry and Cognition in SCA3/MJD	No drug interventions	Not Available	Not Available	unknown_status
NCT04419974	Astrocytic Markers and the Pre-ataxic Period of SCA3/MJD - BIGPRO Study Astrocytes	No drug interventions	Not Available	Not Available	unknown_status
NCT04229823	Natural History of Oculomotor Neurophysiology in Ataxic and Pre-ataxic Carriers of SCA3/MJD	No drug interventions	Not Available	Not Available	unknown_status
NCT02906046	Weight in Lower Limbs Improves Gait Ataxia of in Machado-Joseph Disease Patients	No drug interventions	treatment	Not Available	completed
NCT02039206	The Influence of Deep TMS on Cerebellar Signs in Patients With Machado Joseph Disease	No drug interventions	treatment	2	completed
NCT01811706	Dalfampridine and Gait in Spinocerebellar Ataxias	Dalfampridine	treatment	Not Available	completed
NCT04426149	Clinical Effects of Oral Trehalose In Patients With Spinocerebellar Ataxia 3	No drug interventions	treatment	Not Available	completed
NCT03120013	Rehabilitative Trial With Cerebello-Spinal tDCS in Neurodegenerative Ataxia	No drug interventions	treatment	Not Available	completed
NCT03408080	Open Pilot Trial of BHV-4157	Troriluzole	treatment	3	active_not_recruiting
NCT03487367	Clinical Trial Readiness for SCA1 and SCA3	No drug interventions	Not Available	Not Available	unknown_status
NCT04153110	Cerebello-Spinal tDCS as Rehabilitative Intervention in Neurodegenerative Ataxia	No drug interventions	treatment	Not Available	completed
NCT02175290	Machado-Joseph Disease in Israel	No drug interventions	Not Available	Not Available	unknown_status
NCT01793168	Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford	No drug interventions	Not Available	Not Available	recruiting
NCT02147886	Study To Assess Safety, Tolerability and Efficacy of Intravenous Cabaletta in Patients With Machado-Joseph Disease	Trehalose	treatment	2	completed
NCT04268147	Instrumented Data Exchange for Ataxia Study	No drug interventions	Not Available	Not Available	completed
NCT05826171	Priming Motor Learning Through Exercise in People With Spinocerebellar Ataxia	No drug interventions	treatment	Not Available	active_not_recruiting
NCT05502432	Repetitive Transcranial Magnetic Stimulation in SCA3 Patients	No drug interventions	treatment	Not Available	completed
NCT03701399	Troriluzole in Adult Subjects With Spinocerebellar Ataxia	Troriluzole	treatment	3	active_not_recruiting
NCT05490563	STRIDES - a Clinical Research Study of an Investigational New Drug to Treat Spinocerebellar Ataxia	No drug interventions	treatment	2 / 3	terminated
NCT05557786	Treatment of Transcranial Alternating Current Stimulation（tACS）on Cerebellar Ataxia	No drug interventions	treatment	Not Available	completed
NCT04399265	Efficacy Of Oral Trehalose In Spinocerebellar Ataxia 3	No drug interventions	treatment	Not Available	unknown_status
NCT03885167	Identification of Biomarkers in Spinocerebellar Ataxia 3	No drug interventions	Not Available	Not Available	completed
NCT05822908	A Safety and Pharmacokinetics Trial of VO659 in SCA1, SCA3 and HD	VO659	treatment	1 / 2	recruiting
NCT04301284	Study of CAD-1883 for Spinocerebellar Ataxia	Rimtuzalcap	treatment	2	withdrawn
NCT01060371	Natural History Study of and Genetic Modifiers in Spinocerebellar Ataxias	No drug interventions	Not Available	Not Available	recruiting
NCT00992771	Study to Determine the Safety and Tolerability of Varenicline (Chantix®) in Treating Spinocerebellar Ataxia Type 3	Varenicline	treatment	2	completed
NCT05160558	A Pharmacokinetics and Safety Study of BIIB132 in Adults With Spinocerebellar Ataxia 3	No drug interventions	treatment	1	terminated
NCT01096095	Pilot Study of Safety and Efficacy of Sodium Phenylbutyrate in Spinocerebellar Ataxia Type 3	Phenylbutyric acid	treatment	2	withdrawn
NCT03378414	Umbilical Cord Mesenchymal Stem Cells Therapy (19#iSCLife®-SA) for Patients With Spinocerebellar Ataxia	No drug interventions	treatment	2	not_yet_recruiting