gastrointestinal ulceration (DBCOND0096568)

Identifiers

Synonyms

GI ulceration / Gastro-intestinal ulcer NOS / Gastrointestinal Ulcer / Gastrointestinal ulcers / GI Ulcers / Gastrointestinal ulcer NOS / Ulcer gastrointestinal / Gastrointestinal ulcer (disorder)

Associated Data

Indicated Drugs and Targets

Drug	Description	Targets
Calcium carbonate	An ionic compound used as a calcium supplement or antacid used for the symptomatic relief of heartburn, acid indigestion, and sour stomach.	No drug targets
Etodolac	An NSAID used to treat osteoarthritis and rheumatoid arthritis, as well as acute pain.	Prostaglandin G/H synthase 1target Prostaglandin G/H synthase 2target Cytochrome P450 2C9enzyme UDP-glucuronosyltransferase 1A9enzyme Retinoic acid receptor RXR-alphatarget Albumincarrier Solute carrier family 22 member 6transporter UDP-glucuronosyltransferase 1A3enzyme UDP-glucuronosyltransferase 1A10enzyme UDP-glucuronosyltransferase 2B7enzyme
Famotidine	A histamine H2 receptor antagonist used to treat duodenal ulcers, benign gastric ulcers, GERD, and Zollinger-Ellison syndrome.	Histamine H2 receptortarget Solute carrier family 22 member 2transporter Organic anion transporter 3transporter Multidrug and toxin extrusion protein 1transporter Cytochrome P450 1A2enzyme Solute carrier family 22 member 6transporter
Pentagastrin	A gastrin-like molecule used as a diagnostic aid for the evaluation of gastric acid secretory function, gastric hypersecretion, and Zollinger-Ellison tumors.	Gastrin/cholecystokinin type B receptortarget Cholinesteraseenzyme
Proglumide	Not Annotated	Cholecystokinin receptor type Atarget

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT00797641	European Survey of Non-Variceal Upper Gastro Intestinal Bleeding (NVUGIB)	No drug interventions	Not Available	Not Available	completed
NCT05226221	Gastrointestinal Emergency Surgery: Evaluation of Morbidity and Mortality	No drug interventions	Not Available	Not Available	recruiting