complicated Urinary Tract Infection caused by susceptible bacteria (DBCOND0126067)

Identifiers

Synonyms

Complicated Bacterial Urinary Tract Infections / Complicated urinary tract infection bactieral / Complicated Urinary tract infection bacterial

Associated Data

Indicated Drugs and Targets

Drug	Description	Targets
Ceftolozane	A cephalosporin antibiotic used to treat complicated intra-abdominal infections in combination with metronidazole, complicated urinary tract infections, and hospital-acquired pneumonia.	Penicillin-binding protein 1Btarget Cell division proteintarget Penicillin-binding proteintarget Penicillin-binding protein 1Ctarget Penicillin-binding protein 2target
Ceftriaxone	A broad-spectrum cephalosporin antibiotic used for the treatment of bacterial infections in various locations, such as in the respiratory tract, skin, soft tissue, and urinary tract.	Albumincarrier Solute carrier family 15 member 1transporter Solute carrier family 15 member 2transporter Solute carrier family 22 member 6transporter Organic anion transporter 3transporter Solute carrier family 22 member 11transporter Penicillin-binding protein 2Btarget Glutamine synthetaseenzyme Solute carrier family 22 member 11target Solute carrier family 22 member 6target Organic anion transporter 3target Solute carrier family 15 member 1target ATP-dependent translocase ABCB1transporter
Gentamicin	An aminoglycoside used to treat a wide variety of aerobic infections in the body.	30S ribosomal protein S12target 16S ribosomal RNAtarget NH(3)-dependent NAD(+) synthetasetarget Dihydrofolate reductasetarget 23S ribosomal RNAtarget Bacterial outer membranetarget Cytoplasmic membranetarget Low-density lipoprotein receptor-related protein 2transporter Solute carrier family 22 member 2transporter ATP-binding cassette sub-family C member 2transporter
Levofloxacin	A fluoroquinolone antibiotic used to treat infections caused by susceptible bacteria of the upper respiratory tract, skin and skin structures, urinary tract, and prostate, as well as for post-exposure treatment of inhaled anthrax and the plague.	DNA gyrase subunit Atarget DNA topoisomerase 4 subunit Atarget Solute carrier family 22 member 2transporter ATP-dependent translocase ABCB1transporter Solute carrier family 22 member 4transporter Multidrug and toxin extrusion protein 1transporter Multidrug and toxin extrusion protein 2transporter Cytochrome P450 2C9enzyme Albumincarrier Solute carrier organic anion transporter family member 4C1transporter Solute carrier family 22 member 1transporter Solute carrier organic anion transporter family member 1A2transporter DNA gyrase subunit Atarget DNA gyrase subunit Btarget
Meropenem	A carbapenem antibiotic used to treat a wide variety of infections in the body.	D-alanyl-D-alanine carboxypeptidase DacBtarget Beta-lactamase OXA-10enzyme Dipeptidase 1enzyme
Prulifloxacin	A broad-spectrum fluoroquinolone antibiotic used to treat a variety of susceptible bacterial infections.	Cytochrome P450 1A2enzyme DNA topoisomerase 4 subunit Atarget DNA gyrase subunit Atarget DNA gyrase subunit Btarget

Clinical Trials

Not Available