EGFR L858R (DBCOND0139095)

Identifiers

Synonyms

Not Available

Associated Data

Indicated Drugs and Targets

Not Available

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT04862780	(SYMPHONY) Phase 1/2 Study Targeting EGFR Resistance Mechanisms in NSCLC	Osimertinib Tigozertinib	treatment	1 / 2	active_not_recruiting
NCT05338970	HERTHENA-Lung02: A Study of Patritumab Deruxtecan Versus Platinum-based Chemotherapy in Metastatic or Locally Advanced EGFRm NSCLC After Failure of EGFR TKI Therapy	Platinum	treatment	3	active_not_recruiting
NCT06053099	A Prospective Cohort Study to Evaluate Molecular pRognostic Factors and Resistance Mechanisms to Osimertinib in Adjuvant Treatment of Completely Resected pIB-IIIA Non-small Cell Lung Carcinoma With Common EGFR Mutations (L858R and Del19)	No drug interventions	diagnostic	Not Available	recruiting
NCT05153408	(HARMONY) Study of BLU-701 in EGFR-mutant NSCLC	Carboplatin Osimertinib Pemetrexed	treatment	1	terminated