Oxaprozin is an NSAID used to treat osteoarthritis, rheumatoid arthritis, and juvenile rheumatoid arthritis.
- Mechanism
- Curator reviewed
Anti-inflammatory effects of Oxaprozin are believed to be due to inhibition of cylooxygenase in platelets which leads to the blockage of prostaglandin synthesis. Antipyretic effects may be due to action on the hypothalamus, resulting in an increased peripheral blood flow, vasodilation, and subsequent heat dissipation. Oxaprozin is a non-selective NSAID, with a cell assay system showing lower COX-2 selectivity implying higher COX-1 selectivity.
- Primary indication
- Used to relieve the inflammation, swelling, stiffness, and joint pain associated with rheumatoid arthritis and osteoarthritis.Curator reviewed · 3 structured indications
- Formula / weight
- C18H15NO3 · 293.3166 g/mol (avg)
- First approval
- Canada, 2001 · United States, 1992
- Code names
- WY-21,743
- Brand names
Resolves to
OFPXSFXSNFPTHF-UHFFFAOYSA-NSMILESOC(=O)CCC1=NC(=C(O1)C1=CC=CC=C1)C1=CC=CC=C1What you can answer from here — as of October 01, 2026
Which drugs share a target with Oxaprozin, and which of those have an active Phase 3 trial?
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