- Accession Number
Agents counteracting or neutralizing the action of POISONS.
- ATC Classification
Drug Drug Description Pralidoxime A cholinesterase reactivator used to treat organophosphate poisoning. Flumazenil A benzodiazepine antagonist that is used for the complete or partial reversal of the sedative effects caused by benzodiazepines in various clinical settings, such as induced general anesthesia for diagnostic and therapeutic procedures. Fomepizole An inhibitor of alcohol dehydrogenase used as an antidote in confirmed or suspected methanol or ethylene glycol poisoning. Prussian blue A chelating agent used to reduce the extent of systemic contamination with radioactive cesium and/or radioactive or non-radioactive thallium. Cupric sulfate A compound used as an intravenous copper supplement for Total Parenteral Nutrition (TPN). 4-dimethylaminophenol Not Annotated Leucovorin A folate analog used to treat the toxic effects of methotrexate and other folate antagonists, to treat megaloblastic anemia, and to provide palliative treatment of colorectal cancer. Digoxin Immune Fab (Ovine) An antibody binding fragment which binds digoxin molecules which is used as an antidote to digoxin overdose. Sugammadex A modified gamma cyclodextrin used to reverse neuromuscular blockade induced by vecuronium bromide and rocuronium bromide which are agents used for anesthesia. Nitrous acid An iron binder used to reverse life-threatening acute cyanide poisoning. Hydroxocobalamin A synthetic form of vitamin B12 used to treat vitamin B12 associated disorders and cyanide poisoning. Acetylcysteine A medication that can be used as a mucolytic in patients with certain lung conditions and as an antidote for acetaminophen overdose. Thiosulfuric acid A sulfur donor used sequentially with sodium nitrite for the reversal of life-threatening acute cyanide poisoning. Also used to reduce the risk of ototoxicity associated with cisplatin. Picrotoxin Used internally for relieving respiratory distress. Also for use as an antidote in poisoning by CNS depressants, especially barbiturates. Succimer A mercaptodicarboxylic acid heavy metal chelator used in the treatment of heavy metal poisoning. Penicillamine A chelator used to treat Wilson's disease, cystinuria, and rheumatoid arthritis. Edrophonium A cholinesterase inhibitor used to diagnose and evaluate myasthenia gravis. Attapulgite A veterinary antidiarrheal agent used to treat non-infectious diarrhea in animals. Oglufanide Investigated for use/treatment in hepatitis (viral, C). Ubiquinone Q2 Not Available Activated charcoal A gastric decontamination agent used in emergency clinical settings as a antidote to treat poisonings following excessive oral ingestion of certain medications or poisons. Bentonite Not Annotated Levoleucovorin A folate analog used after high dose methotrexate for osteosarcoma, to reduce the toxic effects of folate analogs, and with 5-fluorouracil in palliative treatment of advanced metastatic colorectal cancer. Montmorillonite A purified clay indicated in the treatment of intestinal pain and diarrhea. Pentetic acid DTPA is widely used in industry and medicine. As a medical agent, it is approved for its use in medical imaging and for the decorporation of internally deposited radionuclides. It... Methionine An amino acid commonly found as a component in total parenteral nutrition. Glutathione For nutritional supplementation, also for treating dietary shortage or imbalance Physostigmine A cholinesterase inhibitor used to treat glaucoma and anticholinergic toxicity. Naloxone An opioid receptor antagonist used to rapidly reverse an opioid overdose. Also included in some drug formulations as an abuse deterrent to prevent injection. Amyl Nitrite A fast acting vasodilator used for rapid relief of angina pectoris. Dimercaprol A chelating agent used as an antidote to arsenic, gold, and mercury poisoning, as well as acute lead poisoning in combination with edetate calcium disodium. Idarucizumab An antibody that binds dabigatran for the reversal of anticoagulant effects of dabigatran. Nalorphine Used to reverse opioid overdose. Protamine A heparin antagonist indicated in the treatment of heparin overdoses, to counteract heparins preoperatively, or during cardiac surgery and dialysis. Obidoxime Not Annotated Methylene blue An oxidation-reduction agent used for the treatment of pediatric and adult patients with acquired methemoglobinemia. Phentolamine An alpha adrenergic antagonist used to reverse soft tissue anesthesia. Prednisolone A glucocorticoid used to treat adrenocortical insufficiency, inflammatory conditions, and some cancers. Ethanol For therapeutic neurolysis of nerves or ganglia for the relief of intractable chronic pain in such conditions as inoperable cancer and trigeminal neuralgia (tic douloureux), in patients for whom neurosurgical... Promethazine A first-generation antihistamine used for the treatment of allergic conditions, nausea and vomiting, and motion sickness. Potassium Iodide An oral antithyroid agent used for the prevention of radioactive iodine uptake into the thyroid gland during a nuclear radiation emergency. Ipecac An emetic agent used to induce vomiting in poisoning. Potassium permanganate Not Annotated Andexanet alfa A recombinant Factor Xa used to reverse anticoagulation caused by rivaroxaban and apixaban. 2,3-Dimercapto-1-propanesulfonic acid Not Annotated Dimercaptosuccinic acid Not Annotated Glucarpidase A carboxypeptidase enzyme used to reduce plasma concentrations of methotrexate in patients with impaired renal function. Nalmefene An opioid antagonist used to reduce alcohol consumption in adults with alcohol dependence and treat and prevent opioid overdose.
- Drugs & Drug Targets