Catalase

BE0001207ProteinHumansCAT

Catalyzes the degradation of hydrogen peroxide (H(2)O(2)) generated by peroxisomal oxidases to water and oxygen, thereby protecting cells from the toxic effects of hydrogen peroxide (PubMed:7882369). It is acted on by 19 drugs in DrugBank.

Gene name
CAT
UniProtKB entry
P04040Swiss-Prot
Cellular location
Peroxisome matrix
Residues / weight
527 residues · 59,756 Da
Also known as
1.11.1.6

Resolves to

Protein
UniProtP04040UniProt nameCATA_HUMAN
Gene
HGNCHGNC:1516NCBI Gene847GenBank1228085GeneCardsCAT
Pharmacology
KEGGhsa:847
Structure
PDB1DGBPDB1DGFPDB1DGG
Drugs

What you can answer from here — as of September 07, 2019

19DrugsApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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2Metabolic reactionsDrug transformations it catalyses, substrate to product
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9GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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43+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Catalase, how selective are they, and which programs against it are still in active trials?

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