3'-phospho-5'-adenylyl sulfate

DB02902ExperimentalSmall molecule

3'-phospho-5'-adenylyl sulfate is a key intermediate in the formation by living cells of sulfate esters of phenols, alcohols, steroids, sulfated polysaccharides, and simple esters, such as choline sulfate. It is... It is formed from sulfate ion and ATP in a two-step process.

Chemical structure of 3'-phospho-5'-adenylyl sulfate
Formula / weight
C10H15N5O13P2S · 507.264 g/mol (avg)
Also known as
3'-phosphoadenosine 5'-phosphosulfate · 3'-phosphoadenylyl sulfate · PAPS

Resolves to

Structure
InChIKeyGACDQMDRPRGCTN-KQYNXXCUSA-NSMILESNC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OS(O)(=O)=O)[C@@H](OP(O)(O)=O)[C@H]1O

What you can answer from here — as of September 20, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action
Listed above
2+ReferencesStructured and connected to the statements they support
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Which drugs share a target with 3'-phospho-5'-adenylyl sulfate, and which of those have an active Phase 3 trial?

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