- Accession Number
Members of the class of compounds composed of AMINO ACIDS joined together by peptide bonds between adjacent amino acids into linear, branched or cyclical structures. OLIGOPEPTIDES are composed of approximately 2-12 amino acids. Polypeptides are composed of approximately 13 or more amino acids. PROTEINS are linear polypeptides that are normally synthesized on RIBOSOMES.
Drug Drug Description Lepirudin A protein-based direct thrombin inhibitor used to reverse and prevent thrombus formation in heparin-induced thrombocytopenia. Denileukin diftitox A recombinant cytotoxic protein based on a combination of diphtheria toxin fragments and interleukin-2 used to treat cutaneous T-cell lymphoma by targeting the interleukin-2 receptor. Bivalirudin A direct thrombin inhibitor used to treat heparin-induced thrombocytopenia and to prevent thrombosis during percutaneous coronary intervention. Leuprolide A peptide-based GnRH receptor superagonist used for the palliative treatment of prostate cancer, uterine leiomyomata, endometriosis, and central precocious puberty. Peginterferon alfa-2a A modified form of recombinant human interferon used to stimulate the innate antiviral response in the treatment of hepatitis B and C viruses. Sermorelin For the treatment of dwarfism, prevention of HIV-induced weight loss Interferon alfa-n1 A purified form of human interferon used to stimulate the innate antiviral response in the treatment of genital warts due to human papilloma virus. Darbepoetin alfa A recombinant form of human erythropoietin used to increase differentiation of progenitor cells to red blood cells in the treatment of anemia. Goserelin A synthetic analog of luteinizing hormone-releasing hormone used to treat breast cancer and prostate cancer by reducing secretion of gonadotropins from the pituitary. Erythropoietin A recombinant form of human erythropoietin used to increase differentiation of progenitor cells to red blood cells in the treatment of anemia. Salmon calcitonin A synthetic peptide form of calcitonin used to inhibit bone resorption in the treatment of hypercalcemia, osteoporosis, and Paget's disease. Interferon alfa-n3 A purified form of human interferon used to stimulate the innate antiviral response in the treatment of genital warts due to human papilloma virus. Pegfilgrastim A recombinant human granulocyte colony stimulating factor used to stimulate the production of neutrophils and prevent febrile neutropenia or infections after myelosuppressive chemotherapy. Sargramostim A modified form of recombinant human granulocyte-macrophage colony stimulating factor used to increase immune cell production after myelosuppressive therapy or bone marrow transplant. Peginterferon alfa-2b A purified form of human interferon used to stimulate the innate antiviral response in the treatment of hepatitis B and C, genital warts, and some cancers. Thyrotropin alfa A recombinant form of thyroid stimulating hormone used in diagnostic testing for thyroid cancer and alongside radioactive agents to destroy thyroid tissue. Anakinra A recombinant form of human interleukin-1 receptor antagonist used in the treatment of rheumatoid arthritis and neonatal-onset multisystem inflammatory disease. Gramicidin D A bactericidal antibiotic used in the treatment of dermatological and ophthalmic infections. Insulin human A recombinant form of human insulin used to control hyperglycemia in diabetes mellitus. Menotropins A purified combination of human luteinizing hormone and follicle stimulating hormone used to treat female infertility. Interferon gamma-1b A form of recombinant human interferon used to treat infections associated with chronic granulomatous disease and to slow the progression of severe malignant osteopetrosis. Desmopressin A synthetic analog of vasopressin used to reduce renal excretion of water in central diabetes insipidus and nocturia. Oprelvekin A form of recombinant interleukin-11 used to stimulate production of megakaryocytes and platelets in patients with or at risk of thrombocytopenia after chemotherapy. Palifermin A form of recombinant human keratinocyte growth factor used to prevent and treat oral mucositis following radiation or chemotherapy. Glucagon A form of recombinant glucagon used to treat hypoglycemia in diabetes mellitus and as a part of gastrointestinal imaging procedures. Aldesleukin A recombinant analog of interleukin-2 used to induce an adaptive immune response in the treatment of renal cell carcinoma. Insulin lispro A modified form of fast-acting insulin used to control hyperglycemia in diabetes mellitus. Insulin glargine A modified form of long-acting or basal insulin used to control hyperglycemia in diabetes mellitus. Cetrorelix A synthetic peptide antagonist of gonadotropin releasing hormone used to prevent luteinizing hormone surges in women undergoing assisted reproduction therapy. Somatotropin A recombinant human growth hormone used as replacement therapy in various conditions of growth failure, growth hormone deficiency, and weakness in children and adults. Abciximab A monoclonal anti-glycoprotein IIb/IIIa receptor antibody used to prevent thrombosis during percutaneous coronary intervention. Indium In-111 satumomab pendetide For diagnosis of extrahepatic malignant cancers Alpha-1-proteinase inhibitor A purified form of human alpha-1 proteinase inhibitor used to treat emphysema patients with associated alpha-1 proteinase inhibitor deficiency. Interferon beta-1a A form of recombinant human interferon used to slow disease progression and reduce the frequency of clinical symptoms in patients who have relapsing multiple sclerosis. Follitropin A form of recombinant human follicle stimulating hormone used to stimulate follicle development in women with primary ovarian hypogonadism and in men with hypogonadotropic hypogonadism. Vasopressin A peptide hormone used to increase blood pressure in patients with vasodilatory shock who are resistant to fluid and catecholamine therapy. Interferon beta-1b A form of recombinant human interferon used to slow the progression of relapsing multiple sclerosis and to reduce the frequency of clinical symptoms. Interferon alfacon-1 A recombinant interferon similar the interferon alfa subtype which is used to treat hepatitis C infections. Insulin pork A purified form of porcine insulin used to control hyperglycemia in diabetes mellitus. Daptomycin A cyclic lipopeptide antibiotic used to treat complicated skin and skin structure infections by susceptible Gram-positive bacteria and bacteremia due to Staphylococcus aureus. Pegvisomant A growth hormone receptor antagonist used to treat acromegaly. Felypressin For use as an alternative to adrenaline as a localising agent, provided that local ischaemia is not essential. Urofollitropin A form of purified human follicle stimulating hormone used to treat infertility in females by inducing follicle development in women without primary ovarian failure. Becaplermin A recombinant form of human platelet-derived growth factor used to treat ulcers due to diabetic neuropathy in the lower extremities when there is adequate blood supply to the area. Octreotide A peptide drug used to treat acromegaly as well as diarrhea associated with metastatic carcinoid tumors and vasoactive intestinal peptide secreting tumors. Abarelix For palliative treatment of advanced prostate cancer. Oxytocin A recombinant hormone used to induce or strengthen uterine contractions in pregnant women to aid in labor and delivery or to control postpartum bleeding. Enfuvirtide An HIV-1 gp41 fusion inhibitor used in patients experiencing HIV-1 replication who are already being treated with other anti-retrovirals. Glutathione For nutritional supplementation, also for treating dietary shortage or imbalance Aspartame Used as a diet supplement and sugar substitute. Pentagastrin A gastrin-like molecule used as a diagnostic aid for the evaluation of gastric acid secretory function, gastric hypersecretion, and Zollinger-Ellison tumors. Bleomycin A chemotherapy agent used to treat various malignancies, including head and neck malignancy, lymphoma, and testicular tumors, among others. Capreomycin An aminoglycoside antibiotic used as an adjunct drug in tuberculosis. Anidulafungin An antifungal used in the treatment of several types of candida infections. Ceruletide Caerulein is used in the treatment of paralytic ileus and as diagnostic aid in pancreatic malfunction. Vancomycin A glycopeptide antibiotic used to treat severe but susceptible bacterial infections such as MRSA (methicillin-resistant Staphylococcus aureus) infections. Caspofungin An echinocandin used to treat a variety of fungal infections. Enalapril A prodrug of an ACE inhibitor used to treat hypertension and congestive heart failure. Bacitracin A cyclic polypeptide antibiotic used to prevent wound infections, treat pneumonia and empyema in infants, and to treat skin and eye infections. Gonadorelin A synthetic GnRH used to test the function of gonadotropes and the pituitary. Nafarelin A gonadotropin releasing hormone agonist used to treat central precocious puberty. Lisinopril An ACE inhibitor used to treat hypertension, heart failure, and acute myocardial infarction. Colistin A polymyxin antibiotic used to treat bacterial infections caused by susceptible Gram negative bacteria. Aminolevulinic acid A porphyrin precursor used to treat actinic keratosis of the face, scalp, and upper extremities, as well as to visualize a glioma. Dactinomycin An actinomycin used to treat a wide variety of cancers. Atazanavir An antiviral protease inhibitor used in combination with other antiretrovirals for the treatment of HIV. Colistimethate An antibiotic indicated for treatment of infections caused by susceptible strains of certain gram-negative bacilli. It is particularly useful for targeting sensitive strains of Pseudomonas aeruginosa. Micafungin An antifungal agent used for the treatment of candidemia, acute disseminated candidiasis, and certain other invasive Candida infections, and for the prophylaxis of Candida infections during stem cell transplantation. Mecasermin A recombinant insulin-like growth factor-1 used for the long-term treatment of growth failure in pediatric patients with primary IGF-1 deficiency or with growth hormone gene deletion due to the development of neutralizing antibodies to GH. Pramlintide An amylin analog used for the management of type 1 and type 2 diabetes mellitus as an adjunct to preprandial insulin therapy in patients without adequate glycemic control of insulin therapy. Carbetocin An oxytocin agent used to control postpartum hemorrhage and bleeding after giving birth. Tetracosactide A diagnostic agent used in the screening of patients presumed to have adrenocortical insufficiency. Corticotropin A diagnostic agent used in the screening of patients presumed to have adrenocortical insufficiency. Insulin aspart A rapid-acting form of insulin used for glycemic control in type 1 and type 2 diabetes mellitus. Insulin detemir A long-acting form of insulin used for glycemic control in type 1 and type 2 diabetes mellitus. Insulin glulisine A short-acting form of insulin used for glycemic control in type 1 and type 2 diabetes mellitus. Spirapril Spirapril is an ACE inhibitor class drug used to treat hypertension. Quinupristin An antibiotic agent used in the treatment of serious vancomycin-resistant Enterococcus faecium bacteremia as well as complicated skin and skin structure infections. Virginiamycin M1 For the treatment of bacterial infections. Chymostatin Not Available Dalfopristin An antibiotic used with quinupristin to treat severe or life-threatening infections of vancomycin-resistant Enterococcus faecium (VREF), and skin infections caused by methicillin susceptible staphylococcus aureus or streptococcus pyogenes. N,N-dimethylglycine Not Available Glycochenodeoxycholic Acid A bile salt formed in the liver from chenodeoxycholate and glycine, usually as the sodium salt. It acts as a detergent to solubilize fats for absorption and is itself absorbed.... Ilomastat Not Available N-(1-carboxy-3-phenylpropyl)phenylalanyl-alpha-asparagine Not Available Mdl 101,146 Not Available Phosphoramidon Not Available N-[(6S)-6-Carboxy-6-(glycylamino)hexanoyl]-D-alanyl-D-alanine Not Available Terlipressin A drug used to treat bleeding caused by esophageal varices. N-(3-Propylcarbamoyloxirane-2-Carbonyl)-Isoleucyl-Proline Not Available GE-2270A Not Available S-octylglutathione Not Available Glutathionylspermidine Not Available Enalkiren Not Available gamma-Glutamylcysteine Not Available Gallichrome Not Available Trypanothione Not Available Z-Pro-Prolinal Not Available Argifin Not Available S-(N-hydroxy-N-bromophenylcarbamoyl)glutathione Not Available Balhimycin Balhimycin is a novel glycopeptide antibiotic. S-Hexylglutathione Not Available Skf 107457 Not Available Cyclotheonamide A Cyclotheonamide A is a cyclic peptide isolated from the marine sponge Theonella. Argadin Not Available Aeruginosin 98-B Not Available Motuporin Motuporin is a toxin isolated from the marine sponge Thenonella swinhoie grey. Virginiamycin S1 One of the components of virginiamycin, a cyclic polypeptide antibiotic complex from streptomyces virginiae, s. Loidensis, s. Mitakaensis, s. Pristina-spiralis, s. Ostreogriseus, and others. It is used to treat infections... Olcegepant For the treatment of migraine headaches. Vapreotide For the treatment of esophageal variceal bleeding in patients with cirrhotic liver disease and has also shown efficacy in the treatment of patients with AIDS-related diarrhea. Nesiritide A recombinant natriuretic peptide used for the treatment of patients with acutely decompensated congestive heart failure who have dyspnea at rest or with minimal activity. Thymalfasin Indicated as an adjuvant for influenza vaccine in elderly patients and as an adjuvant for both influenza and hepatitis B vaccines in chronic hemodialysis patients who failed to achieve adequate... Oritavancin An antibacterial agent used to treat acute bacterial skin and skin structure infections caused by susceptible Gram-positive bacteria. G17DT Intended for the treatment of various forms of cancer. Dirucotide For the treatment of multiple sclerosis (MS). Afamelanotide An injectable subcutaneous implant used to mitigate phototoxicity secondary to erythropoietic protoporphyria (EPP). Pexelizumab For the treatment of inflammation during cardiac surgery. Ramoplanin For the treatment of bacterial infections. Canfosfamide Intended for the treatment of various forms of cancer. Plitidepsin Intended for the treatment of various forms of cancer. Tigapotide For the treatment of late stage Hormone Refractory Prostate Cancer (HRPC) for which no effective therapy currently exists. Lancovutide Investigated for use/treatment in cystic fibrosis and eye disorders/infections. Ularitide Investigated for use/treatment in congestive heart failure. Abaloparatide A parathyroid hormone-related protein (PTHrP) analog used for the treatment of osteoporosis in postmenopausal women with a high risk of fracture. Leptin Investigated for use/treatment in lipodystrophy and obesity. NN344 Investigated for use/treatment in diabetes mellitus type 1 and 2. Aminocandin Investigated for use/treatment in fungal infections. CR665 Investigated for use/treatment in pain (acute or chronic). PM02734 Investigated for use/treatment in cancer/tumors (unspecified) and solid tumors. Elafin Investigated for use/treatment in inflammatory disorders (unspecified). SF1126 For the treatment of various forms of cancer. Interferon alfa Investigated for use/treatment in hepatitis (viral, C), leukemia (lymphoid), leukemia (myeloid), leukemia (unspecified), and melanoma. Glatiramer An immunomodulator used to reduce the frequency of relapses in Multiple Sclerosis (MS). Cintredekin besudotox Investigated for use/treatment in brain cancer. Romiplostim A fusion protein thrombopoietin (TPO) peptide analog that increases platelet counts by binding to and activating the human TPO receptor. Used to treat thrombocytopenia associated with chronic immune thrombocytopenia (ITP). Ciliary neurotrophic factor Investigated for use/treatment in eye disorders/infections, macular degeneration, and retinal disorders (unspecified). NOV-002 Investigated for use/treatment in breast cancer, lung cancer, and ovarian cancer. Corticorelin Investigated for use/treatment in brain cancer and neurologic disorders. Albinterferon Alfa-2B Investigated for use/treatment in hepatitis (viral, C). Tifuvirtide Investigated for use/treatment in acquired immune deficiency syndrome (AIDS) and aids-related infections and HIV infection. ABT-510 Investigated for use/treatment in lymphoma (unspecified), melanoma, and solid tumors. Ezatiostat Investigated for use/treatment in myelodysplastic syndrome. Golotimod Investigated for use/treatment in hepatitis (viral, C), infectious and parasitic disease (unspecified), and tuberculosis. VX-765 Investigated for use/treatment in inflammatory disorders (unspecified) and psoriasis and psoriatic disorders. Telaprevir An NS3/4A viral protease inhibitor used in combination with other antivirals for the curative treatment of chronic Hepatitis C Virus infections. Fibroblast growth factor-1 Investigated for use/treatment in coronary artery disease and peripheral vascular disease. Glypromate Investigated for use/treatment in neurologic disorders. IRX-2 Investigated for use/treatment in cancer/tumors (unspecified), head and neck cancer, and solid tumors. Larazotide Investigated for use/treatment in autoimmune diseases, diabetes mellitus type 1, and gastrointestinal diseases and disorders (miscellaneous). Flovagatran Investigated for use/treatment in thrombosis. Maxy-G34 Investigated for use/treatment in adverse effects (chemotherapy) and neutropenics. Cefilavancin Investigated for use/treatment in bacterial infection, skin infections/disorders, and staph bacterial infections. CYT006-AngQb Investigated for use/treatment in hypertension. Oglufanide Investigated for use/treatment in hepatitis (viral, C). PRO-542 Investigated for use/treatment in acquired immune deficiency syndrome (AIDS) and aids-related infections, HIV infection, and pediatric indications. NBI-6024 Investigated for use/treatment in diabetes mellitus type 1 and pediatric indications. Parathyroid hormone An analog of human parathyroid hormone (PTH) used to treat hypocalcemia caused by hypoparathyroidism. Pegdinetanib Investigated for use/treatment in cancer/tumors (unspecified) and macular degeneration. CTCE-0214 Investigated for use/treatment in adverse effects (chemotherapy), blood (blood forming organ disorders, unspecified), cancer/tumors (unspecified), neutropenics, and vascular diseases. Trofinetide Investigated for use/treatment in traumatic brain injuries. Caplacizumab A von Willebrand factor (vWF)-directed antibody fragment used to treat acquired thrombotic thrombocytopenic purpura (aTTP). IRL-1620 Investigated for use/treatment in cancer/tumors (unspecified). Teicoplanin For the treatment of bacterial infections caused by susceptible microorganisms. Romidepsin A histone deacetylase (HDAC) inhibitor used to treat cutaneous and peripheral T-cell lymphoma. Darinaparsin Investigated for use/treatment in blood (blood forming organ disorders, unspecified), cancer/tumors (unspecified), solid tumors, multiple myeloma, and liver cancer. Talabostat Investigated for use/treatment in lymphoma (non-hodgkin's), leukemia (lymphoid), lung cancer, melanoma, and pancreatic cancer. Icatibant A bradykinin B2 receptor antagonist used to treat acute episodes of swelling and inflammation associated with hereditary angioedema (HAE). Dalbavancin An antibacterial used to treat acute bacterial skin and skin structure infections (ABSSSI) caused by susceptible strains of Gram-positive bacteria. Trafermin Investigated for use/treatment in coronary artery disease, peripheral vascular disease, periodontal disease, bone fractures, entero-related fistulae, and diabetic foot ulcers. Aviptadil Not Annotated Teriparatide A recombinant parathyroid hormone used for the treatment of osteoporosis. Saxagliptin An DPP-4 inhibitor used for the management of type 2 diabetes mellitus. Calcitonin gene-related peptide Investigated for use/treatment in myocardial infarction, heart disease, and asthma. Human C1-esterase inhibitor A C1 inhibitor used to prevent angioedema attacks associated with hereditary angioedema. Endostatin Investigated for use/treatment in cancer/tumors (unspecified), macular degeneration, and diabetic retinopathy. Repifermin Investigated for use/treatment in bone marrow transplant, ulcers, and inflammatory bowel disease. Velafermin Investigated for use/treatment in adverse effects (chemotherapy). Thrombopoietin Investigated for use/treatment in thrombocytopenia. Labradimil Investigated for use/treatment in brain cancer and pediatric indications. Emfilermin Investigated for use/treatment in adverse effects (chemotherapy), reproductive health, and infertility. Anamorelin Investigated for use/treatment in cachexia and anorexia. Liraglutide A GLP-1 analog used in the management of type 2 diabetes mellitus and prevention of cardiovascular complications associated with diabetes. Pasireotide A somatostatin analog used in the treatment of Cushing’s disease, specifically for those patients whom pituitary surgery is not appropriate. Degarelix A GnRH receptor antagonist used in the management of advanced prostate cancer. Buserelin A LHRH agonist used for the palliative treatment of hormone-dependent advanced carcinoma of the prostate gland in males and treatment of endometriosis in females. Saralasin Not Annotated Ganirelix A GnRH antagonist used in assisted reproduction in women undergoing controlled ovarian hyperstimulation to control ovulation by inhibiting the premature LH surges. Histrelin A GnRH agonist found in subcutaneous implants used for the treatment of pediatric patients with central precocious puberty and the palliative treatment of advanced prostate cancer. Lanreotide A somatostatin analog used for the treatment of unresectable, well- or moderately-differentiated, locally advanced or metastatic gastroenteropancreatic neuroendocrine tumors and acromegaly. Tiopronin A thiol agent indicated for the prevention of kidney stone formation in patients with severe homozygous cystinuria. Triptorelin A GnRH agonist indicated for the palliative treatment of advanced prostate cancer. Viomycin Viomycin is an essential component in the drug cocktail currently used to fight infections of Mycobacterium tuberculosis. Thiorphan A potent inhibitor of membrane metalloendopeptidase (enkephalinase). Thiorphan potentiates morphine-induced analgesia and attenuates naloxone-precipitated withdrawal symptoms. DADLE A delta-selective opioid (ANALGESICS, OPIOID). It can cause transient depression of mean arterial blood pressure and heart rate. DPDPE A heterodetic cyclic peptide that is a cyclic enkephalin analogue, having D-penicillaminyl residues located at positions 2 and 5, which form the heterocycle via a disulfide bond. Cholecystokinin For use as a diagnostic aid for evaluation of gallbladder disorders. It is also used in conjunction with secretin in pancreatic insufficiency . Tesamorelin A growth hormone releasing factor (GRF) analog used to reduce excessive abdominal fat in HIV patients who have developed lipodystrophy. Ocriplasmin A proteolytic enzyme used to treat symptomatic vitreomacular adhesion by dissolving the protein matrix responsible for the adhesion between the vitreous and macula. Carfilzomib A proteasome inhibitor used either alone or in conjunction with a chemotherapy regimen to treat patients with relapsed or refractory multiple myeloma. Teduglutide A glucagon-like peptide-2 (GLP-2) analog used to treat patients with Short Bowel Syndrome (SBS) who require parenteral nutritional support. Certolizumab pegol A tumor necrosis factor (TNF) blocker used to treat a variety of autoimmune and autoinflammatory conditions like Crohn's disease, rheumatoid arthritis, active psoriatic arthritis, ankylosing spondylitis, axial spondyloarthritis, and plaque psoriasis. Enviomycin Cyclic basic peptide related to viomycin. It is isolated from an induced mutant of Streptomyces griseoverticillatus var. tuberacticus and acts as an antitubercular agent with less ototoxicity than tuberactinomycin. Albiglutide A GLP-1 agonist used to manage type 2 diabetes mellitus. Dulaglutide A GLP-1 agonist used to manage type 2 diabetes mellitus. Metreleptin A leptin analogue used as an adjunct to diet as replacement therapy to treat the complications of leptin deficiency in patients with congenital or acquired generalized lipodystrophy. Atosiban An inhibitor of oxytocin and vasopressin used to delay imminent preterm birth in pregnant adult women displaying specific clinical observations. Corifollitropin alfa A FSH analogue indicated for Controlled Ovarian Stimulation (COS) in combination with a GnRH antagonist for the development of multiple follicles in women participating in an Assisted Reproductive Technology (ART) program. Corticorelin ovine triflutate A synthetic corticotropin-releasing hormone used for diagnostic purposes in differentiating pituitary and ectopic production of ACTH in patients with ACTH-dependent Cushing's syndrome. Somatrem A recombinant growth hormone used to treat adult growth hormone deficiency and treat disrupted growth in children due to growth hormone insufficiency or deficiency, turner's syndrome, chronic renal failure, and small stature for gestational age. Somatostatin A naturally-occurring peptide hormone used for the symptomatic treatment of acute bleeding from esophageal varices. Ancestim A human stem cell factor used in combination with filgrastim during autologous peripheral blood progenitor cell (PBPC) transplantation to increase PBPC mobilization for improved collection. Methoxy polyethylene glycol-epoetin beta A synthetic erythropoiesis stimulating agent (ESA) used to treat anemia associated with chronic kidney disease. Peginterferon beta-1a An interferon beta used to treat relapsing forms of multiple sclerosis. Chorionic Gonadotropin (Human) A naturally-occurring hormone produced during human placenta used for the treatment of prepubertal cryptorchidism and hypogonadotropic hypogonadism in selected males, and induction of pregnancy in selected infertile women. Sincalide A diagnostic agent used to stimulate gallbladder contraction or pancreatic secretion during diagnostic tests, and accelerate fluoroscopy and x-ray examination of the intestinal tract. Polaprezinc Peptic ulcer disease, dyspepsia . Protirelin A synthetic analogue of thyrotropin-releasing hormone that has been used during diagnostic tests to evaluate function of the thyroid gland. Enalaprilat An antihypertensive agent used for the management of hypertension when oral therapy is not practical. Secretin porcine A secretin hormone used to stimulate pancreatic or gastric secretions to diagnose exocrine pancreas dysfunction, gastrinoma, and abnormalities in the bile and pancreatic ducts. Insulin degludec A long acting insulin used to treat hyperglycemia caused by type 1 and 2 diabetes mellitus. Desirudin Indicated as prophylaxis of deep vein thrombosis for patients undergoing hip replacement surgery. Prezatide Commonly used in cosmetic products for the skin and hair . Emodepside Emodepside is an anthelmintic drug that is effective against a number of gastrointestinal nematodes, is licensed for use in cats and belongs to the class of drugs known as the... Thiostrepton Thiostrepton is a natural cyclic oligopeptide antibiotic, derived from several strains of streptomycetes including Streptomyces azureus and Streptomyces laurentii. Thiostrepton is a natural product of the ribosomally synthesized and post-translationally... Virginiamycin Virginiamycin is a streptogramin antibiotic similar to pristinamycin and quinupristin/dalfopristin. It is a combination of pristinamycin IIA and virginiamycin S1. Virginiamycin is used in the fuel ethanol industry to prevent... Deslorelin Deslorelin acetate is an injectable gonadotropin releasing hormone super-agonist also known as an LHRH agonist. It stops the production of sex hormones. Insulin peglispro Not Annotated Antithrombin III human An alpha-2-glycoprotein used to prevent thromboembolisms in patients with hereditary antithrombin III deficiency. Epoetin delta Epoetin Delta is an ingredient in the EMA-withdrawn product Dynepo. Depreotide Depreotide is an ingredient in the EMA-withdrawn product NeoSpect. Eptotermin alfa A bone morphogenetic protein that is widely expressed during EMBRYONIC DEVELOPMENT. It is both a potent osteogenic factor and a specific regulator of nephrogenesis. Eptotermin alfa is an ingredient in... Dibotermin alfa indicated for the treatment of acute tibia fractures in adults, as an adjunct to standard care using open fracture reduction and intramedullary unreamed nail fixation [FDA Label]. indicated for single-level... Bremelanotide Bremelanotide is indicated to treat premenopausal women with hypoactive sexual desire disorder that is not due to a medical or psychiatric condition, problems with the relationship, or the effects of... Rusalatide acetate Chrysalin has been used in trials studying the treatment of Radius Fracture. Carnosine Carnosine has been investigated for the treatment of Gulf War Illness. Racecadotril An anti-secretory enkephalinase inhibitor useful in the treatment of diarrhea. Setmelanotide Setmelanotide is indicated to treat obesity caused by genetic POMC, PCSK1, or LEPR deficiencies. Acetyl hexapeptide-3 Argireline has been used in trials studying the treatment of wrinkles. Bombesin Bombesin is under investigation in clinical trial NCT01205321 (PET/CT Imaging for Radiation Dosimetry, Plasma Pharmacokinetics, Biodistribution, Safety and Tolerability and Diagnostic Performance of BAY86-7548 in Patients With Prostate Cancer and... Cenderitide Cenderitide is under investigation for the treatment of ST Elevation (STEMI) Myocardial Infarction of Anterior Wall. Birinapant Birinapant has been investigated for the treatment of Myelodysplastic Syndrome (MDS) and Chronic Myelomonocytic Leukemia (CMML). Neuropeptide Y Neuropeptide Y is under investigation for the basic science of Type 2 Diabetes Mellitus. Faldaprevir Faldaprevir has been investigated for the treatment of Chronic Hepatitis C. Lampalizumab Lampalizumab has been used in trials studying the treatment of Geographic Atrophy. Angiotensin II A peptide hormone of the RAAS system used to raise blood pressure in septic or other forms of shock. Astodrimer Astodrimer has been used in trials studying the treatment and prevention of Bacterial Vaginosis. It is a lysine-based dendrimer with naphthalene disulfonic acid surface groups. Valspodar Valspodar has been used in trials studying the treatment of Cancer, Sarcoma, Leukemia, Lymphoma, and Breast Cancer, among others. Alanyl glutamine A dipeptide consisting of alanine and glutamine used for supplementation. BPC-157 Bepecin is under investigation in clinical trial NCT02637284 (PCO-02 - Safety and Pharmacokinetics Trial). Lenomorelin Lenomorelin has been investigated for the treatment and basic science of Cancer, Alcoholism, Metabolism, Hypopituitarism, and Frailty Syndrome, among others. Acyline Acyline has been investigated for the prevention and treatment of Hypogonadism and Contraception. Vosoritide Vosoritide has been used in trials studying the treatment of Achondroplasia. Avotermin Juvista has been investigated for the treatment, prevention, and basic science of Scars, Keloid, and Cicatrix. TAK-448 TAK-448 has been used in trials studying the treatment of Prostate Cancer, Low Testosterone, Prostatic Neoplasms, and Hypogonadotropic Hypogonadism. Elamipretide Elamipretide has been used in trials studying the treatment of Leber's Hereditary Optic Neuropathy. Oprozomib Oprozomib has been used in trials studying the treatment of Solid Tumors, Multiple Myeloma, Waldenstrom Macroglobulinemia, Advanced Hepatocellular Carcinoma, and Advanced Non-Central Nervous System (CNS) Malignancies. Interleukin-7 Interleukin 7 has been used in trials studying the treatment of Metastatic Breast Cancer. Thymosin beta-4 Thymosin Beta 4 has been investigated for the treatment of STEMI, Dry Eye, Diabetes, Pressure Ulcers, and Dry Eye Syndrome, among others. Ibodutant Ibodutant has been used in trials studying the treatment of Irritable Bowel Syndrome and Irritable Bowel Syndrome With Diarrhea. BQ-123 BQ-123 has been investigated for the basic science and treatment of Coronary Artery Disease, Aorto-coronary Bypass Grafting, and ST-Elevation Myocardial Infarction. Nagrestipen Nagrestipen has been used in trials studying the treatment of CANCER, Neoplasm, Metastasis, Radiation Oncology, and Neoplasm Metastasis. Surotomycin Surotomycin has been used in trials studying the treatment of Diarrhea and Clostridium Difficile Infection. It is a benzenebutanoic acid derivative patented by Cubist Pharmaceuticals, Inc. as antibacterial agents for... TT-232 Tln 232 is under investigation in clinical trial NCT00422786 (Phase II Study of CAP-232 in Patients With Refractory Metastatic Renal Cell Carcinoma). Bradykinin Bradykinin has been investigated for the basic science and treatment of Hypertension and Diabetes Type 2. Alisporivir Alisporivir has been used in trials studying the treatment of Hepatitis C and Chronic Hepatitis C. Binetrakin Binetrakin has been used in trials studying the treatment of HIV Infections, Sarcoma, Kaposi, Non-Hodgkin's Lymphoma (NHL), Myelodysplastic Syndrome (MDS), and Leukemia, Acute Myelogenous (AML), among others. OBP-801 OBP-801 has been used in trials studying the treatment of Solid Tumor. Barusiban Barusiban has been used in trials studying the treatment of Infertility and In Vitro Fertilisation (IVF) Treatment. Dulanermin Dulanermin has been used in trials studying the treatment of Colorectal Cancer, Non-Hodgkin's Lymphoma, and Metastatic Colorectal Cancer. Ipamorelin Ipamorelin has been investigated for the treatment of Ileus. Muplestim Muplestim is under investigation in clinical trial NCT00002258 (A Phase I, Open Label Trial to Evaluate the Safety, Tolerance and Biological Effects of SDZ ILE-964 (Recombinant Human Interleukin-3, RhIL-3) in... SCY-635 SCY-635 has been investigated for the treatment of Chronic Hepatitis C and Hepatitis C Infection. Elobixibat Elobixibat has been used in trials studying the treatment and basic science of Dyslipidemia, Constipation, Chronic Constipation, Functional Constipation, and Chronic Idiopathic Constipation. Forigerimod Forigerimod is under investigation for the treatment of Lupus Erythematosus, Systemic. Selepressin Selepressin has been used in trials studying the treatment of Septic Shock. Sarcosine Sarcosine has been investigated for the treatment of Schizophrenia. Molgramostim Molgramostim has been used in trials studying the treatment of Bronchiectasis, Cystic Fibrosis, Pulmonary Alveolar Proteinosis, Acute Respiratory Distress Syndrome, and Autoimmune Pulmonary Alveolar Proteinosis. Nepadutant Nepadutant has been used in trials studying the treatment of Colic, Infantile Colic, and Infantile Functional Gastrointestinal Disorders. Pentetreotide Pentetreotide has been used in trials studying the diagnostic of cushing syndrome. Davunetide Davunetide has been used in trials studying the treatment of Progressive Nonfluent Aphasia, Progressive Supranuclear Palsy, Predicted Tauopathies, Including, Corticobasal Degeneration Syndrome, and Frontotemporal Dementia With Parkinsonism Linked to Chromosome... Sprifermin Sprifermin has been used in trials studying the treatment of Osteoarthritis, Knee and Cartilage Injury of Knee. Nerve Growth Factor Nerve Growth Factor has been used in trials studying the prevention and treatment of Mental Handicap, Alzheimer's Disease, Traumatic Brain Injury, Cerebral Palsy Children, and Delayed Speech Development, among others. Nona-arginine Nona-arginine is under investigation in clinical trial NCT00264706 (PolyArginine Treated vEiN grafTs (PATENT)). Endothelin-1 Endothelin 1 is under investigation in clinical trial NCT00745693 (The Effects of Diesel Exhaust Inhalation on Vascular Function - the Role of Endothelin). Soblidotin Soblidotin has been used in trials studying the treatment of Sarcoma, Lung Cancer, and Unspecified Adult Solid Tumor, Protocol Specific. Relamorelin Relamorelin has been investigated for the treatment and basic science of Gastroparesis, Gastric Motility, Diabetes Mellitus, Parkinson's Disease, and Chronic Constipation, among others. Balugrastim Balugrastim has been used in trials studying the treatment of Solid Tumors. LTX-109 LTX-109 has been investigated for the treatment of Atopic Dermatitis, Mild Eczema/Dermatoses, and Gram-positive, Skin Infections. Dolastatin 10 Dolastatin 10 has been used in trials studying the treatment of Sarcoma, Leukemia, Lymphoma, Liver Cancer, and Kidney Cancer, among others. Tiplimotide Tiplimotide has been used in trials studying the treatment of Multiple Sclerosis. LTX-315 LTX-315 has been used in trials studying the treatment of Cancer, Lymphoma, Melanoma, Carcinoma, and Breast Cancer, among others. Zoptarelin doxorubicin Zoptarelin doxorubicin has been used in trials studying the treatment of Breast Cancer, Ovarian Cancer, Prostate Cancer, Endometrial Cancer, and Urothelial Carcinoma, among others. Somatoprim Somatoprim is under investigation for the treatment of Acromegaly. CMX-2043 CMX-2043 has been used in trials studying the treatment and prevention of Non STEMI, Unstable Angina, Stable Coronary Artery Disease, and Percutaneous Coronary Intervention. Pancreatic Polypeptide Pancreatic Polypeptide has been investigated for the treatment of Diabetes Mellitus, Type 1. GS-9256 GS-9256 has been used in trials studying the treatment of HCV Infection and Chronic Hepatitis C Infection. Interleukin-10 Interleukin-10 has been used in trials studying the prevention and treatment of Vasculitis, Pancreatitis, Bile Duct Diseases, Pancreatic Diseases, and Gallbladder Diseases, among others. Bleomycin A6 Bleomycin A6 (also known as boanmycin) has been used in trials studying the treatment of Squamous Cell Lung Cancer. It was developed in China as an antineoplastic antibiotic. This drug... Cibinetide Cibinetide has been used in trials studying the basic science of Depression. Urocortin-2 Urocortin 2 has been investigated for the basic science of Heart Failure and Cardiovascular Disease. Rotigaptide Rotigaptide is under investigation for the basic science of Heart Disease and Vascular Disease. 9-(N-methyl-L-isoleucine)-cyclosporin A 9-(N-methyl-L-isoleucine)-cyclosporin A (NIM811) has been used in trials studying the treatment of Chronic Hepatitis C Genotype-1 Relapse. Lenograstim The drug is used to reduce the risk of life-threatening infection in patients with neutropenia, particularly after cytotoxic chemotherapy. Lenograstim is indicated as a treatment to reduce the duration of... Lipegfilgrastim A medication used to reduce the duration of chemotherapy-induced neutropenia and incidence of febrile neutropenia in cytotoxic chemotherapy. Arginine glutamate Two amino acids indicated in the treatment of hyperammonemia and in combination for total parenteral nutrition. Alsactide Not Annotated Sulglicotide Not Annotated Ornipressin Not Annotated Tyrothricin A topical antibiotic with broad spectrum activity against Gram positive bacteria and some fungal infections. Angiotensinamide Not Annotated Calcium pangamate Not Annotated Mifamurtide A muramyl dipeptide derivative used to treat high grade, resectable, non-metastatic osteosarcoma after surgical resection. Pristinamycin Not Annotated Elcatonin Not Annotated Demoxytocin Not Annotated Paclitaxel poliglumex Not Annotated Semaglutide A glucagon-like peptide 1 receptor agonist used to improve glycemic control in type 2 diabetes mellitus. Lutetium Lu 177 dotatate A radiolabeled somatostatin analog used to treat somatostatin receptor positive gastroenteropancreatic neuroendocrine tumors. Taspoglutide Taspoglutide is a pharmaceutical drug, a glucagon-like peptide-1 agonist (GLP-1 agonist), under investigation for treatment of type 2 diabetes being codeveloped by Ipsen and Roche. In September 2010 Roche halted... Teverelix Investigated for use/treatment in benign prostatic hyperplasia, endometriosis, and prostate cancer. Valinomycin A cyclododecadepsipeptide ionophore antibiotic produced by Streptomyces fulvissimus and related to the enniatins. It is composed of 3 moles each of L-valine, D-alpha-hydroxyisovaleric acid, D-valine, and L-lactic acid linked alternately... Basifungin Basifungin, also known as aureuobacidin A, is a phosphorylceramide synthase inhibitor , . Reversin 121 Reversin 121 is a hydrophobic peptide chemosensitizer that can reverse P-glycoprotein-mediated multidrug resistance. Interleukin-1 alpha, human recombinant Not Annotated Basic Fibroblast Growth Factor Basic Fibroblast Growth Factor is not currently approved for any FDA or Health Canada approved indications. Nepidermin Not Annotated Insulin-like growth factor II The insulin-like growth factor II is a well-characterized neutral peptide believed to be secreted by the liver and to circulate in the blood. This factor presents effects related to growth... Filgrastim A form of recombinant human granulocyte colony stimulating factor used to induce the production of granulocytes and lower infection risk after myelosuppressive therapy. Secretin human A secretin hormone used to stimulate pancreatic or gastric secretions to diagnose exocrine pancreas dysfunction, gastrinoma, and abnormalities in the bile and pancreatic ducts. Lypressin Not Annotated acetylleucyl-leucyl-norleucinal Not Available S-(2,4-dinitrophenyl)glutathione Not Available Glycocholic acid The glycine conjugate of cholic acid. It acts as a detergent to solubilize fats for absorption and is itself absorbed. Glutathione disulfide An ingredient of ophthalmic irrigation solutions used during ophthalmological procedures. Voclosporin A calcineurin inhibitor for the treatment of lupus nephritis (LN) in patients diagnosed with systemic lupus erythematosus (SLE). Indium In-111 pentetreotide Indium In 111 pentetreotide (Octreoscan) has been used in trials studying the diagnostic of SARCOIDOSIS, Solid Tumors, and cushing syndrome. Ozarelix Ozarelix has been used in trials studying the treatment of Prostate Cancer, Benign Prostatic Hypertrophy, and Benign Prostatic Hyperplasia (BPH). Plecanatide A laxative used to treat chronic idiopathic constipation and IBS with constipation. Peptide YY (3-36) Investigated for use/treatment in metabolic disease and obesity. Cyclosporine A steroid-sparing immunosuppressant used in organ and bone marrow transplants as well as inflammatory conditions such as ulcerative colitis, rheumatoid arthritis, and atopic dermatitis. DiaPep 277 Investigated for use/treatment in diabetes mellitus type 1, autoimmune diseases, and diabetes mellitus type 2. Luteinizing hormone Not Annotated Polymyxin B A polymyxin antibiotic used to treat a wide variety of infections in the body. Narlaprevir Not Annotated Regramostim Investigated for use/treatment in adverse effects (chemotherapy) and bone marrow transplant. Sar9, Met (O2)11-Substance P Investigated for use/treatment in acute respiratory distress syndrome (ARDS) and viral infection. Peginterferon lambda-1a Peginterferon lambda-1a is under investigation in clinical trial NCT01754974 (Safety and Efficacy Study of Peginterferon Lambda-1a vs. Peginterferon Alfa-2a, Plus Ribavirin in Subjects With Genotype 1 Hepatitis C). Avexitide Avexitide is under investigation in clinical trial NCT02996812 (Evaluation of Single Ascending Doses of Subcutaneous Exendin 9-39 in Patients With Post-Bariatric Hypoglycemia). Demplatin pegraglumer Demplatin pegraglumer is under investigation in clinical trial NCT02043288 (Combination Therapy With NC-6004 and Gemcitabine Versus Gemcitabine Alone in Pancreatic Cancer). Procalcitonin Procalcitonin is under investigation in clinical trial NCT03440060 (Procalcitonin-guided Antibiotic Therapy During Severe Exacerbation of COPD). Human interleukin-2 Human interleukin-2 is under investigation in clinical trial NCT03475134 (TIL-ACT After NMA Chemo With IL-2 and Nivo Rescue in mMEL). Vobarilizumab Vobarilizumab is under investigation in clinical trial NCT02101073 (ALX-0061 Phase I Bioavailability Study in Healthy Volunteers). Aspartyl-alanyl-diketopiperazine Aspartyl-alanyl-diketopiperazine is under investigation in clinical trial NCT03349645 (An Open Label Extension Study to Assess the Safety of Long-Term Treatment With Ampion for Severe OA of the Knee). Dalantercept Dalantercept is under investigation in clinical trial NCT00996957 (Study of ACE-041 in Patients With Advanced Solid Tumors or Relapsed/Refractory Multiple Myeloma). Human interferon beta A polypeptide drug used in the treatment of relapsing forms of Multiple Sclerosis (MS). Recombinant CD40-ligand Recombinant CD40-ligand is under investigation in clinical trial NCT00053391 (Vaccine Therapy in Treating Patients With Stage III or Stage IV Melanoma). Ipafricept Ipafricept is under investigation in clinical trial NCT01608867 (A Dose Escalation Study of OMP-54F28 in Subjects With Solid Tumors). Somapacitan A human growth hormone analog subcutaneous injection indicated for adults with growth hormone deficiency. Leridistim Leridistim is under investigation in clinical trial NCT00004215 (Leridistim Compared With Filgrastim in Treating Older Patients With Acute Myeloid Leukemia). Somatropin pegol Somatropin pegol is under investigation in clinical trial NCT00715689 (Dose Study in Growth Hormone Deficient Adults Investigating Safety, Pharmacokinetics and Pharmacodynamics of NNC126-0083). Interferon alfa-2c Interferon alfa-2c is under investigation in clinical trial NCT00485563 (A Phase II Study of EC17 (Folate-hapten Conjugate) in Patients With Progressive Metastatic Renal Cell Carcinoma). Gastric inhibitory polypeptide Gastric inhibitory polypeptide is under investigation in clinical trial NCT03081676 (The Effect of GIP and GLP-1 on Insulin and Glucagon Secretion in Patients With HNF1A-diabetes Treated With or Without Sulphonylurea). Avidin Avidin is under investigation in clinical trial NCT00345618 (Clinical Study Assessing Idrabiotaparinux Sodium Injections Once-weekly in Pulmonary Embolism Therapeutic Approach). Antipain Antipain is a serine/cysteine protease inhibitor originally isolated from various strains of actinomycetes. Early studies investigated the potential for antipain to alter DNA damage and chromosomal aberrations in irradiated cells... Thyrotropin A medication indicated in thyroid stimulation before radioactive iodine ablation or for thyroid imaging. Edratide Edratide is under investigation in clinical trial NCT00203151 (A Study to Evaluate the Tolerability, Safety and Effectiveness of Edratide in the Treatment of Lupus). VM4-037 VM4-037 is under investigation in clinical trial NCT00884520 (An Exploratory, Open Label, Multi-Center, Non-Randomized Study of [F-18]VM4-037). PL-3994 PL-3994 is under investigation in clinical trial NCT01304628 (Cross-Over Study of Subcutaneous Study Drug for the Treatment of Patients With Mild to Moderate Asthma). ALT-801 ALT-801 is under investigation in clinical trial NCT01478074 (ALT-801-activated Natural Killer Cells After FLAG Induction for Acute Myeloid Leukemia). Tucotuzumab celmoleukin Tucotuzumab celmoleukin is under investigation in clinical trial NCT00016237 (Interleukin-2 Combined With Monoclonal Antibody Therapy in Treating Patients With Kidney, Bladder, or Lung Cancer That Has Not Responded to Previous... Lorukafusp alfa Lorukafusp alfa is under investigation in clinical trial NCT01334515 (Biological Therapy, Sargramostim, and Isotretinoin in Treating Patients With Relapsed or Refractory Neuroblastoma). Etanercept A protein therapy based on the binding fragment of the tumour necrosis factor alpha receptor used to treat severe rheumatoid arthritis and moderate to severe plaque psoriasis. Eptifibatide A peptide-based antagonist for glycoprotein IIb/IIIa used in the medical management of myocardial infarction and as an adjunct to percutaneous coronary intervention. Exenatide A GLP-1 agonist used in the management of type 2 diabetes mellitus. rGLP-1 Investigated for use/treatment in congestive heart failure and diabetes mellitus type 2. Contulakin-G Investigated for use/treatment in pain (acute or chronic). Telavancin An antibacterial agent used in the treatment of complicated skin and skin structure infections and types of hospital-acquired bacterial pneumonia. Omiganan Investigated for use/treatment in bacterial infection and rosacea. Fusafungine Fusafungine is an antibiotic from Fusarium lateririum, and is used for the treatment of respiratory infections. Eftrenonacog alfa A recombinant Factor IX used to treat and prevent bleeding in hemophilia B. Angiotensin 1-7 TXA127 has been investigated for the treatment of Miscellaneous Peripheral Blood Cell Abnormalities. Endostar Endostar is under investigation for the treatment of Nasopharyngeal Carcinoma. Endostar has been investigated for the treatment of Non-small Cell Lung Cancer. Rapastinel Rapastinel has been used in trials studying the treatment of Depressive Disorder, Major and Obsessive-Compulsive Disorder (OCD). Danegaptide Danegaptide has been investigated for the treatment of Focus of Study is STEMI. Dusquetide Dusquetide has been used in trials studying the treatment of Oral Mucositis. Solnatide Solnatide has been used in trials studying the treatment of Acute Lung Injury. Luspatercept An erythroid maturation agent used to treat anemia secondary to beta thalassemia in patients requiring regular red blood cell transfusions. Aclerastide Aclerastide has been investigated for the treatment of Diabetic Foot, Diabetic Foot Ulcers, and Foot Ulcer, Diabetic. Pirnabine Pirnabine has been used in trials studying the treatment of Chronic Idiopathic Constipation. Albusomatropin Albusomatropin has been used in trials studying the treatment of Growth Hormone-Deficiency and Growth Hormone Deficiency. Neladenoson bialanate Neladenoson bialanate has been investigated for the treatment of Heart Failure. Malacidin A Malacidin A is being investigated for its antibiotic action and has potential for use as an antibacterial agent in the future . Malacidin B Malacidin B is being investigated for its antibiotic action and has potential for use as an antibacterial agent in the future . Murepavadin Murepavadin is under investigation in clinical trial NCT02110459 (Pharmacokinetics and Safety of POL7080 in Patients With Renal Impairment). Gancotamab Gancotamab is under investigation in clinical trial NCT02213744 (MM-302 Plus Trastuzumab vs. Chemotherapy of Physician's Choice Plus Trastuzumab in HER2-Positive Locally Advanced/Metastatic Breast Cancer Patients). Bempegaldesleukin Bempegaldesleukin is under investigation in clinical trial NCT03729245 (A Study of NKTR-214 in Combination With Nivolumab Compared With the Investigator's Choice of a Tyrosine Kinase Inhibitor (TKI) Therapy (Either Sunitinib... BPI-3016 BPI-3016 is under investigation in clinical trial NCT03188848 (Dose Escalating Study of BPI-3016 in Healthy Subjects). Pegilodecakin Pegilodecakin is under investigation in clinical trial NCT03382912 (Study of Pegilodecakin (LY3500518) With Nivolumab Compared to Nivolumab Alone Second-line Tx in Participants With Metastatic Non-Small Cell Lung Cancer). Tirzepatide Tirzepatide is under investigation in clinical trial NCT03311724 (A Study of Tirzepatide (LY3298176) in Participants With Type 2 Diabetes). Mibenratide Mibenratide is under investigation in clinical trial NCT01798745 (A Study to Assess the Pharmacokinetics and Pharmacodynamics of JNJ-54452840 in Participants With Heart Failure and Anti-beta1-adrenergic Receptor Autoantibodies). Pegbelfermin Pegbelfermin is under investigation in clinical trial NCT03486899 (A Study of Experimental Medication BMS-986036 in Adults With Nonalcoholic Steatohepatitis (NASH) and Stage 3 Liver Fibrosis). Balixafortide Balixafortide is under investigation in clinical trial NCT03786094 (Pivotal Study in HER2 Negative, Locally Recurrent or Metastatic Breast Cancer). Tallimustine An alkylating agent previously investigated for it's antitumor activity but was stopped due to severe myelotoxicity. Dotatate gallium Ga-68 Dotatate gallium 68 is one of the most prominent radiopharmaceuticals used in imaging with positron emission tomography. It binds to the somatostatin-2 receptor which is usually overexpressed in many neuroendocrine... JE-2147 Not Available Arylomycin A2 Not Available S-benzylglutathione Not Available Ornithine An amino acid commonly found as a component in total parenteral nutrition. Cyclo(his-pro) Not Available Echinomycin Echinomycin is a cytotoxic polypeptide quinoxaline antibiotic isolated from Streptomyces echinatus that binds to DNA and inhibits RNA synthesis. Atrial natriuretic peptide Not Annotated S-(4-nitrobenzyl)glutathione Not Available TRV-120027 TRV120027 has been used in trials studying the treatment of Heart Failure and Kidney Disease. NNZ-2591 NNZ-2591 (cyclo-L-glycyl-L-2-allylproline) is an investigational synthetic analog of cyclic glycine-proline (cGP), a breakdown product of human insulin-like growth factor 1 (IGF-1), that has been chemically modified to increase its half-life,... S-Methyl glutathione Not Available Kelatorphan Not Available ACV tripeptide Not Available Cyclo(prolylglycyl) Not Available Nitrilotriacetic acid Nitrilotriacetic acid is a derivative of acetic acid, N(CH2COOH)3. It is a complexing (sequestering) agent that forms stable complexes with Zn2+. (From Miall's Dictionary of Chemistry, 5th ed.) Amphomycin Not Annotated Edodekin alfa Edodekin alfa is under investigation in clinical trial NCT01468896 (Cetuximab and Recombinant Interleukin-12 in Treating Patients With Squamous Cell Carcinoma of the Head and Neck That Is Recurrent, Metastatic, or... Viral Macrophage-Inflammatory Protein Viral macrophage inflammatory protein-II (vMIP) is a highly basic protein and human chemokine analog encoded by human herpesvirus-8. The structure of vMIP consists of 71 residues and is a monomer... Interferon Kappa Interferon kappa is a subclass of type I interferon mediating host defence which consists of 207 amino acids and has 30% homology with others of the same class as it... Trefoil Factor 2 The trefoil factor 2 (TFF2) peptide is a low-molecular weight protein and one of the three trefoil-motif-containing proteins. They are expressed predominantly in gastric tissues with the source for them... Copper oxodotreotide Cu-64 A Cu labeled somatostatin analog used in positron emission tomography to detect certain types of neuroendocrine tumors. Polygeline A medication used for plasma volume expansion. Glycylglutamine An ingredient in amino acid solutions for parenteral nutrition. Glycyltyrosine An ingredient in amino acid solutions for parenteral nutrition. Iseganan Iseganan is under investigation in clinical trial NCT00022373 (Iseganan Hydrochloride in Preventing Oral Mucositis in Patients Who Are Undergoing Radiation Therapy for Head and Neck Cancer). SER-100 SER-100 is under investigation in clinical trial NCT01987284 (SER100 in Isolated Systolic Hypertension). Gallium Ga-68 gozetotide A radiopharmaceutical agent used in the diagnosis of prostate-specific membrane antigen (PSMA) positive lesions in male patients during positron emission tomography. Dapirolizumab pegol Dapirolizumab pegol is under investigation in clinical trial NCT02804763 (A Phase 2 Efficacy and Safety Study of Dapirolizumab Pegol (DZP) in Systemic Lupus Erythematosus). Dopastatin Dopastatin is under investigation in clinical trial NCT04335357 (TBR-760 in Adult Patients With Non-functioning Pituitary Adenomas). Dynorphin Dynorphin is under investigation in clinical trial NCT00000244 (Effects of Dynorphin 1-13 on Heroin Addiction - 1). VEGFR2-169 VEGFR2-169 is under investigation in clinical trial NCT00655785 (Antiangiogenic Peptide Vaccine Therapy With Gemcitabine in Treating Patient With Pancreatic Cancer (Phase1/2)). C-peptide C-peptide is under investigation in clinical trial NCT00278980 (Effect of C-peptide on Diabetic Peripheral Neuropathy). Kisspeptin-10 Kisspeptin-10 is under investigation in clinical trial NCT03771326 (KP-10 and Insulin Secretion in Men). Parathyroid Hormone-Related Protein 1-36 Parathyroid Hormone-Related Protein 1-36 is under investigation in clinical trial NCT00853723 (Comparison Study of Pthrp and PTH to Treat Osteoporosis). Pegylated synthetic human c-peptide Not Annotated Pexiganan Pexiganan is under investigation in clinical trial NCT01594762 (Pexiganan Versus Placebo Control for the Treatment of Mild Infections of Diabetic Foot Ulcers). Rezafungin Rezafungin is under investigation in clinical trial NCT04368559 (Study of Rezafungin Compared to Standard Antimicrobial Regimen for Prevention of Invasive Fungal Diseases in Adults Undergoing Allogeneic Blood and Marrow Transplantation). Amlintide A medication used in combination with corticosteroids for the treatment of hemorrhoids. Tengonermin Tengonermin, also known as NGR-hTNF, is a vascular-targeting drug. It is a recombinant protein and peptide-targeted agent consisting of the human Tumour Necrosis Factor-α (TNF-α) conjugated with the CNGRCG peptide....
- Drugs & Drug Targets