N-{[4-(but-2-yn-1-yloxy)phenyl]sulfonyl}-5-methyl-D-tryptophan

DB07233ExperimentalSmall molecule

N-{[4-(but-2-yn-1-yloxy)phenyl]sulfonyl}-5-methyl-D-tryptophan: Overview.

Chemical structure of N-{[4-(but-2-yn-1-yloxy)phenyl]sulfonyl}-5-methyl-D-tryptophan
Formula / weight
C22H22N2O5S · 426.485 g/mol (avg)

Resolves to

Compound
ChEMBLCHEMBL527018PubChem42627769
Structure
InChIKeySFVPXERGVLDWIS-OAQYLSRUSA-NSMILES[H][C@](CC1=CNC2=C1C=C(C)C=C2)(NS(=O)(=O)C1=CC=C(OCC#CC)C=C1)C(O)=O
Targets
P78536ADAM17

What you can answer from here — as of April 02, 2025

1Protein targetEach mapped to UniProt, with action and pharmacological action
Listed above
1+ReferenceStructured and connected to the statements they support
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Which drugs share a target with N-{[4-(but-2-yn-1-yloxy)phenyl]sulfonyl}-5-methyl-D-tryptophan, and which of those have an active Phase 3 trial?

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