Bile acid receptor

BE0001777ProteinHumansNR1H4

Ligand-activated transcription factor. It is acted on by 26 drugs in DrugBank.

Gene name
NR1H4
UniProtKB entry
Q96RI1Swiss-Prot
Cellular location
Nucleus
Residues / weight
486 residues · 55,914 Da
Also known as
BAR · Farnesoid X-activated receptor · Farnesol receptor HRR-1 · FXR · HRR1

Resolves to

Protein
UniProtQ96RI1UniProt nameNR1H4_HUMAN
Gene
HGNCHGNC:7967NCBI Gene9971GenBank1546084GeneCardsNR1H4
Pharmacology
IUPHAR/GtoPdb603KEGGhsa:9971
Structure
PDB1OSHPDB3BEJPDB3DCT
Drugs

What you can answer from here — as of September 07, 2019

26DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
2Clinical trialsTrials of drugs acting on it, by phase and status
Sign in
12GO termsFunction, process and component, as structured annotations
Sign in
2Pfam domainsDomain architecture mapped to Pfam families and clans
Sign in
102+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Bile acid receptor, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In