Solute carrier organic anion transporter family member 1A2

BE0003642ProteinHumansSLCO1A2

Na(+)-independent transporter that mediates the cellular uptake of a broad range of organic anions such as the endogenous bile salts cholate and deoxycholate, either in their unconjugated or conjugated forms (taurocholate and glycocholate), at the... It is acted on by 98 drugs in DrugBank.

Gene name
SLCO1A2
UniProtKB entry
P46721Swiss-Prot
Cellular location
Cell membrane
Residues / weight
670 residues · 74,144 Da
Also known as
OATP · OATP-1 · OATP-A · OATP1 · OATP1A2

Resolves to

Protein
UniProtP46721UniProt nameSO1A2_HUMAN
Gene
HGNCHGNC:10956NCBI Gene6579GenBank885978GeneCardsSLCO1A2
Pharmacology
IUPHAR/GtoPdb1219KEGGhsa:6579
Drugs

What you can answer from here — as of September 07, 2019

98DrugsApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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7GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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207+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Solute carrier organic anion transporter family member 1A2, how selective are they, and which programs against it are still in active trials?

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