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Monopotassium phosphate is an ionic compound used for electrolyte replenishment and total parenteral nutrition (TPN) therapy. Monopotassium phosphate, MKP, (also potassium dihydrogenphosphate, KDP, or monobasic potassium phosphate), KH2PO4, is a soluble salt of potassium and the dihydrogen phosphate ion.
- Mechanism
- Curator reviewed
hosphorus has a number of important functions in the biochemistry of the body. The bulk of the body's phosphorus is located in the bones, where it plays a key role in osteoblastic and osteoclastic activities. Enzymatically catalyzed phosphate-transfer reactions are numerous and vital in the metabolism of carbohydrate, lipid and protein, and a proper concentration of the anion is of primary importance in assuring an orderly biochemical sequence. ln addition, phosphorus plays an important role in modifying steady-state tissue concentrations of calcium. Phosphate ions are important buffers of the intracellular fluid, and also play a primary role in the renal excretion of the hydrogen ion. Oral administration of inorganic phosphates increases serum phosphate levels. Phosphates lower urinary calcium levels in idiopathic hypercalciuria.
- Primary indication
- Used in buffers (determination of pH, pharmaceutical production, urinary acidifier, paper processing, baking powder, and food), nutrient solutions, yeast foods, special liquid fertilizers, sonar systems and other electronic applications; Used as a nutritional supplement in...Curator reviewed · 4 structured indications
- Formula / weight
- H2KO4P · 136.0855 g/mol (avg)
- First approval
- Canada, 1998 · United States, 1979
- Also known as
- Monobasic potassium phosphate · Monopotassium dihydrogen monophosphate · Monopotassium dihydrogen orthophosphate · Monopotassium dihydrogen phosphate · Monopotassium monophosphate
- Code names
- E-340(I) · INS-340(I) · INS NO.340(I)
- Brand names
- Dextrose and Electrolyte No. 75
- Ionosol-MB
- Isolyte S
- Isolyte S pH 7.4
- Isoplate
- K-phos
- K-phos Neutral
- K-phos No 2
- Tis-U-sol
Resolves to
GNSKLFRGEWLPPA-UHFFFAOYSA-MSMILES[K+].OP(O)([O-])=OWhat you can answer from here — as of July 06, 2026
Which drugs share a target with Monopotassium phosphate, and which of those have an active Phase 3 trial?