Glutathione disulfide

DB03310ApprovedSmall molecule

Glutathione disulfide is an ingredient of ophthalmic irrigation solutions used during ophthalmological procedures. A GLUTATHIONE dimer formed by a disulfide bond between the cysteine sulfhydryl side chains during the course of being oxidized.

Chemical structure of Glutathione disulfide
Mechanism
Curator reviewed
Formula / weight
C20H32N6O12S2 · 612.631 g/mol (avg)
First approval
Canada, 2002 · United States, 2013
Also known as
Glutathione disulphide · GSSG · Oxidized glutathione · Oxiglutatione
Brand names
  • Bss Ophthalmic Solution

Resolves to

Compound
UNIIULW86O013HCAS27025-41-8ChEMBLCHEMBL1372ChEBI17858PubChem65359KEGGD00031
Clinical / RWD
RxNorm25953
Structure
InChIKeyYPZRWBKMTBYPTK-BJDJZHNGSA-NSMILESN[C@@H](CCC(=O)N[C@@H](CSSC[C@H](NC(=O)CC[C@H](N)C(O)=O)C(=O)NCC(O)=O)C(=O)NCC(O)=O)C(O)=O
Targets
P00390GSRP10620MGST1P28161GSTM2

What you can answer from here — as of September 12, 2026

5Protein targetsEach mapped to UniProt, with action and pharmacological action
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4Clinical trialsPhase, status and sponsor resolved per trial
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1Structured indicationCondition, population, route and combination as fields, not prose
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5Marketed productsAcross 3 countries and 4 labellers
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6+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Glutathione disulfide, and which of those have an active Phase 3 trial?

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