Methyl undecenoyl leucinate

DB11272ApprovedSmall moleculeMelanin Synthesis Inhibitor

Methyl undecenoyl leucinate is an active ingredient in whitening creams. It is an α-MSH antagonist that inhibits melanin synthesis and tyrosinase activity and reduces expression of various melanogenic genes.

Chemical structure of Methyl undecenoyl leucinate
Formula / weight
C18H33NO3 · 311.466 g/mol (avg)

Resolves to

Clinical / RWD
Structure
InChIKeyICMAWHHKHYZNDA-INIZCTEOSA-NSMILESCOC(=O)[C@H](CC(C)C)NC(=O)CCCCCCCCC=C

What you can answer from here — as of April 02, 2025

2Marketed productsAcross 1 country and 1 labeller
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Which companies are running trials of Methyl undecenoyl leucinate, in which indications and phases, and which of those programs are still active?

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