Amithiozone

DB12829InvestigationalSmall molecule

Amithiozone has been used in trials studying the treatment of Mycobacterium Avium-intracellulare Infection.

Mechanism: Pharmacologically active on Cyclopropane mycolic acid synthase 2 and Cyclopropane mycolic acid synthase 1
Curator reviewed
Formula / weight: C₁₀H₁₂N₄OS · 236.29 g/mol (avg)
Also known as: Thioacetazone
Code names: NSC-3550 · RP 4207 · SDT 1041 · SQ-2321 · TB I-698

Resolves to

Compound

UNIIMMG78X7SSRCAS104-06-3ChEMBLCHEMBL375492PubChem9568512

Clinical / RWD

ATCJ04AK07ATCJ04AM04

Structure

InChIKeySRVJKTDHMYAMHA-WUXMJOGZSA-NSMILESCC(=O)NC1=CC=C(\C=N\NC(N)=S)C=C1

Targets

P9WPB5cmaA2P9WPB7cmaA1P14679TYR

What you can answer from here — as of July 07, 2026

3Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

58Drug interactionsStructured to mechanism, not free text

3Clinical trialsPhase, status and sponsor resolved per trial

2Marketed productsAcross 1 country and 1 labeller

2ATC codesIncluding every combination product, plus 9 drug categories

3+ReferencesStructured and connected to the statements they support

Which drugs share a target with Amithiozone, and which of those have an active Phase 3 trial?

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