Mavatrep

DB12875InvestigationalSmall molecule

Mavatrep has been used in trials studying the treatment of Osteoarthritis, Knee.

Mechanism: Pharmacologically active on Transient receptor potential cation channel subfamily V member 1
Curator reviewed
Formula / weight: C₂₅H₂₁F₃N₂O · 422.451 g/mol (avg)
Code names: JNJ-39439335

Resolves to

Compound

Structure

InChIKeyORDHXXHTBUZRCN-NTEUORMPSA-NSMILESCC(C)(O)C1=CC=CC=C1C1=CC=C2N=C(NC2=C1)\C=C\C1=CC=C(C=C1)C(F)(F)F

Targets

What you can answer from here — as of June 15, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

3Clinical trialsPhase, status and sponsor resolved per trial

5+ReferencesStructured and connected to the statements they support

Which drugs share a target with Mavatrep, and which of those have an active Phase 3 trial?

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