MK-0873

DB13029InvestigationalSmall molecule

MK-0873 has been used in trials studying the treatment of Rheumatoid Arthritis.

Chemical structure of MK-0873
Mechanism
Curator reviewed
Formula / weight
C25H18N4O3 · 422.444 g/mol (avg)
Code names
MK0873

Resolves to

Compound
UNIIK4KAC9XCCOCAS500355-52-2ChEMBLCHEMBL485629PubChem9919680
Structure
InChIKeyJJWKQXNHYDJXKF-UHFFFAOYSA-NSMILES[O-][N+]1=CC(=CC=C1)C#CC1=CC(=CC=C1)N1C=C(C(=O)NC2CC2)C(=O)C2=CC=CN=C12
Targets
Q08499PDE4DQ07343PDE4BP27815PDE4A

What you can answer from here — as of June 15, 2026

4Protein targetsEach mapped to UniProt, with action and pharmacological action
Listed above
1Drug interactionStructured to mechanism, not free text
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4Clinical trialsPhase, status and sponsor resolved per trial
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12+ReferencesStructured and connected to the statements they support
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Which drugs share a target with MK-0873, and which of those have an active Phase 3 trial?

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