This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Summary

Technetium Tc-99m etifenin is a radiopharmaceutical indicated in imaging studies of the liver and biliary tract.

Generic Name
Technetium Tc-99m etifenin
DrugBank Accession Number
DB13183
Background

Not Available

Type
Small Molecule
Groups
Experimental
Structure
Thumb
Weight
Average: 739.607
Monoisotopic: 739.191129968
Chemical Formula
C32H41N4O10Tc
Synonyms
  • Technetium (99m Tc) etifenin
  • Technetium (99mTc) etifenin

Pharmacology

Indication

Not Available

Pharmacology
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Contraindications & Blackbox Warnings
Contraindications
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
Adverseeffects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Products

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Categories

ATC Codes
V09DA02 — Technetium (99mtc) etifenin
Drug Categories
Chemical TaxonomyProvided by Classyfire
Description
This compound belongs to the class of organic compounds known as alpha amino acid amides. These are amide derivatives of alpha amino acids.
Kingdom
Organic compounds
Super Class
Organic acids and derivatives
Class
Carboxylic acids and derivatives
Sub Class
Amino acids, peptides, and analogues
Direct Parent
Alpha amino acid amides
Alternative Parents
Alpha amino acids / Anilides / N-arylamides / Dicarboxylic acids and derivatives / Trialkylamines / Secondary carboxylic acid amides / Amino acids / Organic transition metal salts / Carboxylic acids / Carboximidic acids
show 5 more
Substituents
Alpha-amino acid / Alpha-amino acid amide / Amine / Amino acid / Anilide / Aromatic homomonocyclic compound / Benzenoid / Carbonyl group / Carboxamide group / Carboximidic acid
show 18 more
Molecular Framework
Not Available
External Descriptors
Not Available
Affected organisms
Not Available

Chemical Identifiers

UNII
1R72G5JPE8
CAS number
72950-39-1
InChI Key
WITRLSOYTCFMKJ-FCHARDOESA-K
InChI
InChI=1S/2C16H22N2O5.Tc/c2*1-3-11-6-5-7-12(4-2)16(11)17-13(19)8-18(9-14(20)21)10-15(22)23;/h2*5-7H,3-4,8-10H2,1-2H3,(H,17,19)(H,20,21)(H,22,23);/p-3/i;;1+1
IUPAC Name
2-[(carboxymethyl)({[(2,6-diethylphenyl)carbamoyl]methyl})amino]acetic acid (98Tc)technetium 2-[(carboxylatomethyl)({[(Z)-(2,6-diethylphenyl)carboximidato]methyl})amino]acetate
SMILES
[98Tc].CCC1=CC=CC(CC)=C1NC(=O)CN(CC(O)=O)CC(O)=O.CCC1=CC=CC(CC)=C1\N=C(/[O-])CN(CC([O-])=O)CC([O-])=O

References

General References
  1. INVIMA Product Authorization: Ehida (technetium Tc-99m etifenin) for intravenous injection [Link]
PubChem Compound
131704327
PubChem Substance
347829284

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
PowderIntravenous20 mg
Prices
Not Available
Patents
Not Available

Properties

State
Solid
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility0.182 mg/mLALOGPS
logP2.21ALOGPS
logP-0.46ChemAxon
logS-3.3ALOGPS
pKa (Strongest Acidic)3.25ChemAxon
pKa (Strongest Basic)2.57ChemAxon
Physiological Charge-1ChemAxon
Hydrogen Acceptor Count6ChemAxon
Hydrogen Donor Count3ChemAxon
Polar Surface Area106.94 Å2ChemAxon
Rotatable Bond Count18ChemAxon
Refractivity85.8 m3·mol-1ChemAxon
Polarizability33.09 Å3ChemAxon
Number of Rings2ChemAxon
Bioavailability0ChemAxon
Rule of FiveNoChemAxon
Ghose FilterNoChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSNot Available

Drug created at June 14, 2017 21:39 / Updated at June 05, 2021 09:12