Reversin 121

DB14072ExperimentalSmall molecule

Reversin 121 is a hydrophobic peptide chemosensitizer that can reverse P-glycoprotein-mediated multidrug resistance.

Mechanism: Pharmacologically active on ATP-dependent translocase ABCB1
Curator reviewed
Formula / weight: C₃₄H₄₇N₃O₉ · 641.762 g/mol (avg)

Resolves to

Compound

Structure

InChIKeySVNKEDMVAQBLLN-SVBPBHIXSA-NSMILESCC(C)(C)OC(=O)N[C@@H](CC(=O)OCC1=CC=CC=C1)C(=O)N[C@@H](CCCCNC(=O)OCC1=CC=CC=C1)C(=O)OC(C)(C)C

Targets

What you can answer from here — as of April 02, 2025

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

5+ReferencesStructured and connected to the statements they support

Which drugs share a target with Reversin 121, and which of those have an active Phase 3 trial?

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