Sodium 1,2-Dipalmitoyl-sn-glycero-3-phospho-(1'-rac-glycerol)
This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Brand Names
- Lumason
- Generic Name
- Sodium 1,2-Dipalmitoyl-sn-glycero-3-phospho-(1'-rac-glycerol)
- DrugBank Accession Number
- DB14105
- Background
Not Available
- Type
- Small Molecule
- Groups
- Approved, Experimental
- Structure
Structure for Sodium 1,2-Dipalmitoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (DB14105)
- Weight
- Average: 744.964
Monoisotopic: 744.49172986 - Chemical Formula
- C38H74NaO10P
- Synonyms
- 1,2-dipalmitoyl-sn-glycero-3-phosphorylglycerol sodium salt
- L-DPPG-Na
- R-DPPG-Na
- External IDs
- MG-6060LS
Pharmacology
- Indication
Not Available
Accelerate your drug discovery research with the industry’s only fully connected ADMET dataset, ideal for:Accelerate your drug discovery research with our fully connected ADMET dataset- Contraindications & Blackbox Warnings
Contraindications & Blackbox WarningsWith our commercial data, access important information on dangerous risks, contraindications, and adverse effects.Our Blackbox Warnings cover Risks, Contraindications, and Adverse Effects- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Reduce medical errorsand improve treatment outcomes with our comprehensive & structured data on drug adverse effects.Reduce medical errors & improve treatment outcomes with our adverse effects data- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- No interactions found.
Products
Comprehensive & structured drug product infoFrom application numbers to product codes, connect different identifiers through our commercial datasets.Easily connect various identifiers back to our datasets- Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image LumaSon Sodium 1,2-Dipalmitoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (.19 mg/1mg) + 1,2-Distearoyllecithin (.19 mg/1mg) + Sulfur hexafluoride (60.7 mg/1mg) Injection, powder, lyophilized, for suspension Intravenous; Intravesical Bracco Diagnostics Inc 2021-04-01 Not applicable US 
LumaSon Sodium 1,2-Dipalmitoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (.19 mg/1mg) + 1,2-Distearoyllecithin (.19 mg/1mg) + Sulfur hexafluoride (60.7 mg/1mg) Kit Intravenous; Intravesical Bracco Diagnostics Inc 2015-01-15 Not applicable US LumaSon Sodium 1,2-Dipalmitoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (.19 mg/1mg) + 1,2-Distearoyllecithin (.19 mg/1mg) + Sulfur hexafluoride (60.7 mg/1mg) Kit Intravenous; Intravesical Bracco Suisse SA 2015-01-15 Not applicable US
Categories
- Drug Categories
- Not Available
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 841B886EJ7
- CAS number
- 200880-41-7
- InChI Key
- LDWIWSHBGAIIMV-ODZMYOIVSA-M
- InChI
- InChI=1S/C38H75O10P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-37(41)45-33-36(34-47-49(43,44)46-32-35(40)31-39)48-38(42)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h35-36,39-40H,3-34H2,1-2H3,(H,43,44);/q;+1/p-1/t35?,36-;/m1./s1
- IUPAC Name
- sodium (2R)-1-[(2,3-dihydroxypropyl phosphono)oxy]-3-(hexadecanoyloxy)propan-2-yl hexadecanoate
- SMILES
- [Na+].[H][C@@](COC(=O)CCCCCCCCCCCCCCC)(COP([O-])(=O)OCC(O)CO)OC(=O)CCCCCCCCCCCCCCC
References
Clinical Trials
- Clinical Trials
Phase Status Purpose Conditions Count 4 Enrolling by Invitation Diagnostic Crohn's Disease (CD) 1 4 Recruiting Diagnostic Abdominal Injuries / Accidental Fall / Motor Vehicle Injury / Physical Abuse 1 4 Recruiting Diagnostic Hepatic Disease 1 4 Recruiting Diagnostic Renal Malignant Tumor 1 4 Recruiting Diagnostic Trauma Abdomen 1 4 Terminated Diagnostic Liver Biopsy 1 4 Withdrawn Diagnostic Bone Marrow Transplant Complications / Sinusoidal Obstruction Syndrome (SOS) / Stem Cell Transplant Complications / Veno Occlusive Disease, Hepatic 1 4 Withdrawn Diagnostic Neonatal Post-Hemorrhagic Hydrocephalus 1 3 Completed Diagnostic Coronary Artery Disease (CAD) 2 3 Terminated Diagnostic Cardiovascular Disease (CVD) 1
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Injection, powder, lyophilized, for suspension Intravenous; Intravesical Kit Intravenous; Intravesical - Prices
- Not Available
- Patents
Patent Number Pediatric Extension Approved Expires (estimated) Region US5686060 No 1997-11-11 2017-11-11 US US10232061 No 2019-03-19 2038-07-06 US US10335502 No 2019-07-02 2038-07-06 US
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 0.000119 mg/mL ALOGPS logP 8.32 ALOGPS logP 10.94 ChemAxon logS -6.8 ALOGPS pKa (Strongest Acidic) 1.89 ChemAxon pKa (Strongest Basic) -3 ChemAxon Physiological Charge -1 ChemAxon Hydrogen Acceptor Count 6 ChemAxon Hydrogen Donor Count 2 ChemAxon Polar Surface Area 151.65 Å2 ChemAxon Rotatable Bond Count 40 ChemAxon Refractivity 194.19 m3·mol-1 ChemAxon Polarizability 88.81 Å3 ChemAxon Number of Rings 0 ChemAxon Bioavailability 0 ChemAxon Rule of Five No ChemAxon Ghose Filter No ChemAxon Veber's Rule No ChemAxon MDDR-like Rule No ChemAxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
Drug created on June 21, 2018 16:23 / Updated on June 12, 2020 16:53