Annexin A2

BE0001170ProteinHumansANXA2

Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It is acted on by 4 drugs in DrugBank.

Gene name
ANXA2
UniProtKB entry
P07355Swiss-Prot
Cellular location
Secreted, extracellular space, extracellular matrix, basement membrane
Residues / weight
339 residues · 38,604 Da
Also known as
Annexin II · Annexin-2 · ANX2 · ANX2L4 · CAL1H

Resolves to

Protein
UniProtP07355UniProt nameANXA2_HUMAN
Gene
HGNCHGNC:537NCBI Gene302GenBank219910GeneCardsANXA2
Pharmacology
KEGGhsa:302
Structure
PDB1W7BPDB1XJLPDB2HYU
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
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32GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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27+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Annexin A2, how selective are they, and which programs against it are still in active trials?

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