SB-1578

DB15294InvestigationalSmall molecule

SB-1578 is under investigation in clinical trial NCT01235871 (A Single and Multiple-Dose Study of SB1578).

Mechanism: Pharmacologically active on Receptor-type tyrosine-protein kinase FLT3, Macrophage colony-stimulating factor 1 receptor, and Tyrosine-protein kinase JAK2
Curator reviewed
Formula / weight: C₂₆H₃₀N₄O₄ · 462.55 g/mol (avg)
Code names: SB-1578

Resolves to

Compound

Structure

InChIKeyNNXDIGHYPZHXTR-ONEGZZNKSA-NSMILESC(CN1CCCC1)OC1=C2COC\C=C\COCC3=CC=C(O3)C3=CC=NC(NC(C=C1)=C2)=N3

Targets

What you can answer from here — as of June 15, 2026

3Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

1Clinical trialPhase, status and sponsor resolved per trial

11+ReferencesStructured and connected to the statements they support

Which drugs share a target with SB-1578, and which of those have an active Phase 3 trial?

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