Ezobresib

DB15435InvestigationalSmall molecule

BMS-986158 is under investigation in clinical trial NCT02419417 (Study of BMS-986158 in Subjects With Select Advanced Cancers).

Mechanism: Pharmacologically active on Bromodomain-containing protein 4, Bromodomain-containing protein 2, and Bromodomain-containing protein 3
Curator reviewed
Formula / weight: C₃₀H₃₃N₅O₂ · 495.627 g/mol (avg)
Code names: BMS-986158

Resolves to

Compound

Structure

InChIKeyKGERZPVQIRYWRK-GDLZYMKVSA-NSMILESCN1N=NC(C)=C1C1=CC2=C(N=C1)C1=C(C=C(C=C1)C(C)(C)O)N2[C@@H](C1CCOCC1)C1=CC=CC=C1

Targets

What you can answer from here — as of July 08, 2026

3Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

4Clinical trialsPhase, status and sponsor resolved per trial

3+ReferencesStructured and connected to the statements they support

Which drugs share a target with Ezobresib, and which of those have an active Phase 3 trial?

Create a free account or log in to explore the full data card.