Alexitol sodium

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Summary

Alexitol sodium is an antacid indicated to treat indigestion, heartburn, and ulcers.

Generic Name
Alexitol sodium
DrugBank Accession Number
DB15908
Background

Not Available

Type
Small Molecule
Groups
Experimental
Structure
Weight
Average: 309.158
Monoisotopic: 309.0372809
Chemical Formula
C7H15AlNaO10
Synonyms
  • Alexitol sodium
  • Sodium polyhydroxyaluminium monocarbonate hexitol complex

Pharmacology

Indication

Not Available

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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Products

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International/Other Brands
Acriflex / Actal
Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
ACTAL PLUS TabletAlexitol sodium (200 mg) + Magnesium hydroxide (152 mg) + Simethicone (25 mg)TabletOralA. MENARINI SINGAPORE PTE. LTD.2020-09-08Not applicableMalaysia flag
ACTAL PLUS TABLETAlexitol sodium (200 mg) + Magnesium hydroxide (152 mg) + Simethicone (25 mg)TabletOralA. MENARINI SINGAPORE PTE. LTD.1993-03-29Not applicableSingapore flag

Categories

Drug Categories
Not Available
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
JDN69ZV6XV
CAS number
66813-51-2
InChI Key
KFVBMBOOLFSJHV-UHFFFAOYSA-K
InChI
InChI=1S/C6H14O6.CH2O3.Al.Na.H2O/c7-1-3(9)5(11)6(12)4(10)2-8;2-1(3)4;;;/h3-12H,1-2H2;(H2,2,3,4);;;1H2/q;;+3;+1;/p-3
IUPAC Name
aluminium(3+) sodium hexane-1,2,3,4,5,6-hexol hydroxide carbonate
SMILES
[OH-].[Na+].[Al+3].[O-]C([O-])=O.OCC(O)C(O)C(O)C(O)CO

References

General References
  1. NPRA: Actal Plus (Alexitol Sodium, Magnesium Hydroxide, Simethicone) Oral Tablet [Link]
ChemSpider
32699987
RxNav
236340

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
TabletOral
TabletOral152 mg
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility229.0 mg/mLALOGPS
logP-2.7ALOGPS
logP-3.7Chemaxon
logS0.1ALOGPS
pKa (Strongest Acidic)12.59Chemaxon
pKa (Strongest Basic)-3Chemaxon
Physiological Charge0Chemaxon
Hydrogen Acceptor Count6Chemaxon
Hydrogen Donor Count6Chemaxon
Polar Surface Area121.38 Å2Chemaxon
Rotatable Bond Count5Chemaxon
Refractivity38.4 m3·mol-1Chemaxon
Polarizability16.96 Å3Chemaxon
Number of Rings0Chemaxon
Bioavailability1Chemaxon
Rule of FiveNoChemaxon
Ghose FilterNoChemaxon
Veber's RuleNoChemaxon
MDDR-like RuleNoChemaxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available
Chromatographic Properties
Collision Cross Sections (CCS)
Not Available

Drug created at November 20, 2020 18:07 / Updated at May 22, 2021 06:02