Alexitol sodium
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This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Explore a selection of our essential drug information below, or:
Identification
- Summary
Alexitol sodium is an antacid indicated to treat indigestion, heartburn, and ulcers.
- Generic Name
- Alexitol sodium
- DrugBank Accession Number
- DB15908
- Background
Not Available
- Type
- Small Molecule
- Groups
- Experimental
- Structure
- Weight
- Average: 309.158
Monoisotopic: 309.0372809 - Chemical Formula
- C7H15AlNaO10
- Synonyms
- Alexitol sodium
- Sodium polyhydroxyaluminium monocarbonate hexitol complex
Pharmacology
- Indication
Not Available
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- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
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- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Products
- Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.
- International/Other Brands
- Acriflex / Actal
- Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image ACTAL PLUS Tablet Alexitol sodium (200 mg) + Magnesium hydroxide (152 mg) + Simethicone (25 mg) Tablet Oral A. MENARINI SINGAPORE PTE. LTD. 2020-09-08 2024-06-28 Malaysia ACTAL PLUS TABLET Alexitol sodium (200 mg) + Magnesium hydroxide (152 mg) + Simethicone (25 mg) Tablet Oral A. MENARINI SINGAPORE PTE. LTD. 1993-03-29 Not applicable Singapore
Categories
- Drug Categories
- Not Available
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- JDN69ZV6XV
- CAS number
- 66813-51-2
- InChI Key
- KFVBMBOOLFSJHV-UHFFFAOYSA-K
- InChI
- InChI=1S/C6H14O6.CH2O3.Al.Na.H2O/c7-1-3(9)5(11)6(12)4(10)2-8;2-1(3)4;;;/h3-12H,1-2H2;(H2,2,3,4);;;1H2/q;;+3;+1;/p-3
- IUPAC Name
- aluminium(3+) sodium hexane-1,2,3,4,5,6-hexol hydroxide carbonate
- SMILES
- [OH-].[Na+].[Al+3].[O-]C([O-])=O.OCC(O)C(O)C(O)C(O)CO
References
- General References
- NPRA: Actal Plus (Alexitol Sodium, Magnesium Hydroxide, Simethicone) Oral Tablet [Link]
- External Links
Clinical Trials
- Clinical Trials
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Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Tablet Oral Tablet Oral 152 mg - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 229.0 mg/mL ALOGPS logP -2.7 ALOGPS logP -3.7 Chemaxon logS 0.1 ALOGPS pKa (Strongest Acidic) 12.59 Chemaxon pKa (Strongest Basic) -3 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 6 Chemaxon Hydrogen Donor Count 6 Chemaxon Polar Surface Area 121.38 Å2 Chemaxon Rotatable Bond Count 5 Chemaxon Refractivity 38.4 m3·mol-1 Chemaxon Polarizability 16.96 Å3 Chemaxon Number of Rings 0 Chemaxon Bioavailability 1 Chemaxon Rule of Five No Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
- Chromatographic Properties
Collision Cross Sections (CCS)
Not Available
Drug created at November 20, 2020 18:07 / Updated at May 22, 2021 06:02