Linperlisib

DB17235InvestigationalSmall molecule

Linperlisib: Overview.

Mechanism: Pharmacologically active on Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
Curator reviewed
Formula / weight: C₂₈H₃₇FN₆O₅S · 588.7 g/mol (avg)
Also known as: Methanesulfonamide, n-(5-(6-fluoro-8-((4-(1-hydroxy-1-methylethyl)-1-piperidinyl)methyl)-2-(4-morpholinyl)-4-quinazolinyl)-2-methoxy-3-pyridinyl)- · N-(5-(6-fluoro-8-((4-(2-hydroxypropan-2-yl) piperidin-1-yl)methyl)-2-morpholinoquinazolin-4-yl)-2-methoxypyridin-3-)methanesulfonamide · N-[5-(6-fluoro-8-{[4-(2-hydroxypropan-2-yl) piperidin-1-yl]methyl}-2-morpholinoquinazolin-4-yl)-2-methoxypyridin-3-]methanesulfonamide · N-[5-(6-fluoro-8-{[4-(2-hydroxypropan-2-yl)piperidin-1-yl]methyl}-2-morpholinoquinazolin-4-yl)-2-methoxypyridin-3-yl]methanesulfonamide · Pi3k.delta.-in-2
Code names: YY-20394

Resolves to

Compound

Structure

InChIKeyNVWKNQGHVMMAJW-UHFFFAOYSA-NSMILESCOC1=NC=C(C=C1NS(C)(=O)=O)C1=C2C=C(F)C=C(CN3CCC(CC3)C(C)(C)O)C2=NC(=N1)N1CCOCC1

Targets

What you can answer from here — as of July 08, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

34Clinical trialsPhase, status and sponsor resolved per trial

6+ReferencesStructured and connected to the statements they support

Which drugs share a target with Linperlisib, and which of those have an active Phase 3 trial?

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