Zipalertinib

DB18763InvestigationalSmall molecule

Zipalertinib: Overview.

Chemical structure of Zipalertinib
Mechanism
Curator reviewed
Formula / weight
C23H20N6O · 396.454 g/mol (avg)
Code names
CLN-081 · TAS-6417

Resolves to

Compound
UNIIT4YMU8TW9HCAS1661854-97-2ChEMBLCHEMBL4650281ChEBI233402PubChem117918742
Structure
InChIKeyMKCYPWYURWOKST-INIZCTEOSA-NSMILESCC1=C[C@@H](CN2C3=NC=NC(N)=C3C(=C12)C1=CC2=CC=CC=C2N=C1)NC(=O)C=C
Targets
P00533EGFR

What you can answer from here — as of September 23, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action
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7Clinical trialsPhase, status and sponsor resolved per trial
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3+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Zipalertinib, and which of those have an active Phase 3 trial?

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