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Erzotabart

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Identification

Generic Name
Erzotabart
DrugBank Accession Number
DB19063
Background

Erzotabart is under investigation in clinical trial NCT04824794 (GEN3014 Safety Trial in Relapsed or Refractory Hematologic Malignancies).

Type
Biotech
Groups
Investigational
Biologic Classification
Protein Based Therapies
Monoclonal antibody (mAb)
Protein Chemical Formula
Not Available
Protein Average Weight
Not Available
Sequences
Not Available
Synonyms
  • gamma1 heavy chain Homo sapiens (1-450) [VH (Homo sapiens IGHV1-69*04 (93.8%) -(IGHD) -IGHJ3*02 (93.8%), CDR-IMGT [8.8.14] (26-33.51-58.97-110)) (1-121)-Homo sapiens IGHG1*03, G1m3, nG1m1 CH1 R120 CH3 E12, M14, IGHG1v34 CH3 G109 (CH1 R120 (218) (122-219)
  • Immunoglobulin g1 (434-glycine), anti-(human cd38 antigen) (human monoclonal gen3014 .gamma.1-chain), disulfide with human monoclonal gen3014 .kappa.-chain, dimer
  • Immunoglobulin G1-kappa, anti-[Homo sapiens CD38 (ADP-ribosyl cyclase 1, cyclic ADP-ribose hydrolase 1, cADPr hydrolase 1, cADPR1)], Homo sapiens monoclonal antibody
External IDs
  • GEN 3014
  • GEN-3014
  • GEN3014
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Pharmacology

Indication

Not Available

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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Categories

Drug Categories
Not Available
Chemical TaxonomyProvided by Classyfire
Description
Not Available
Kingdom
Organic Compounds
Super Class
Organic Acids
Class
Carboxylic Acids and Derivatives
Sub Class
Amino Acids, Peptides, and Analogues
Direct Parent
Peptides
Alternative Parents
Not Available
Substituents
Not Available
Molecular Framework
Not Available
External Descriptors
Not Available
Affected organisms
Not Available

Chemical Identifiers

UNII
1I9AVY2IS7
CAS number
2430792-01-9

References

General References
Not Available
Not Available

Clinical Trials

Clinical Trials
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1, 2RecruitingTreatmentAcute Myeloid Leukemia / Diffuse Large B-Cell Lymphoma (DLBCL) / Relapsed or Refractory Multiple Myeloma (RRMM)1somestatusstop reasonjust information to hide

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Drug created at July 03, 2024 14:12 / Updated at July 04, 2024 03:36