Fosclevudine alafenamide
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This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Explore a selection of our essential drug information below, or:
Identification
- Generic Name
- Fosclevudine alafenamide
- DrugBank Accession Number
- DB19113
- Background
Fosclevudine alafenamide is under investigation in clinical trial NCT05238844 (A Study of Safety and Efficacy of ATI-2173 and Vebicorvir in Combination With Tenofovir Disoproxil Fumarate in Subjects With Chronic Hepatitis B Virus Infection).
- Type
- Small Molecule
- Groups
- Investigational
- Structure
- Weight
- Average: 529.458
Monoisotopic: 529.162544687 - Chemical Formula
- C22H29FN3O9P
- Synonyms
- L-alanine, n-((s)-hydroxyphenoxyphosphinyl)-, 1-methylethyl ester, 5'-ester with 1-(2-deoxy-2-fluoro-.beta.-l-arabinofuranosyl)-5-methyl-2,4(1h,3h)-pyrimidinedione
- External IDs
- AT-2173
- ATI 2173
- ATI-2173
- ATI2173
Pharmacology
- Indication
Not Available
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- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Categories
- Drug Categories
- Not Available
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 77AP23J0GH
- CAS number
- 1951476-79-1
- InChI Key
- FTMNZJASLMPPNW-MHFVGYLCSA-N
- InChI
- InChI=1S/C22H29FN3O9P/c1-12(2)33-21(29)14(4)25-36(31,35-15-8-6-5-7-9-15)32-11-16-18(27)17(23)20(34-16)26-10-13(3)19(28)24-22(26)30/h5-10,12,14,16-18,20,27H,11H2,1-4H3,(H,25,31)(H,24,28,30)/t14-,16-,17+,18+,20-,36+/m0/s1
- IUPAC Name
- SMILES
- CC(C)OC(=O)[C@H](C)N[P@](=O)(OC[C@@H]1O[C@@H]([C@H](F)[C@H]1O)N1C=C(C)C(=O)NC1=O)OC1=CC=CC=C1
References
- General References
- Not Available
- External Links
- ChemSpider
- 129234903
- ChEMBL
- CHEMBL5095214
Clinical Trials
- Clinical Trials
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Explore 4,000+ rare diseases, orphan drugs & condition pairs, clinical trial why stopped data, & more. Preview package Phase Status Purpose Conditions Count Start Date Why Stopped 100+ additional columns Unlock 175K+ rows when you subscribe.View sample data2 Terminated Treatment Chronic Hepatitis B Infection 1 somestatus stop reason just information to hide 2 Terminated Treatment Chronic Hepatitis B Infection / Hepatitis D 1 somestatus stop reason just information to hide 1 Completed Treatment Chronic Hepatitis B Infection 1 somestatus stop reason just information to hide 1 Completed Treatment Drug Drug Interaction (DDI) 2 somestatus stop reason just information to hide 1 Terminated Treatment Chronic Hepatitis B Infection 1 somestatus stop reason just information to hide
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
- Chromatographic Properties
Collision Cross Sections (CCS)
Not Available
Drug created at July 04, 2024 15:41 / Updated at July 05, 2024 04:35