R906289

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
R906289
DrugBank Accession Number
DB19126
Background

R906289 is under investigation in clinical trial NCT05308264 (Study of R289 in Participants With Lower-risk Myelodysplastic Syndromes (LR MDS)).

Type
Small Molecule
Groups
Investigational
Structure
Weight
Average: 623.57
Monoisotopic: 623.152746148
Chemical Formula
C25H28F2N7O6PS
Synonyms
Not Available
External IDs
  • R 289
  • R 906289
  • R-289
  • R-906289
  • R289
  • R906289

Pharmacology

Indication

Not Available

Reduce drug development failure rates
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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Products

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Product Ingredients
IngredientUNIICASInChI Key
R906289 sodiumNY79N95ME2Not AvailableFMFDQKQUOHAXDN-AQHGIAEGSA-M

Categories

Drug Categories
Not Available
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
FZC82L3L2B
CAS number
2602614-45-7
InChI Key
ZSSREAXVWYYKJC-ZCQHSFHSSA-N
InChI
InChI=1S/C25H28F2N7O6PS/c1-3-39-17-6-4-16(5-7-17)34-12-19(23(32-34)22-18(26)8-9-21(27)31-22)29-24(35)20-13-42-25(30-20)15-10-28-33(11-15)14(2)40-41(36,37)38/h8-14,16-17H,3-7H2,1-2H3,(H,29,35)(H2,36,37,38)/t14?,16-,17-
IUPAC Name
SMILES
CCO[C@H]1CC[C@@H](CC1)N1C=C(NC(=O)C2=CSC(=N2)C2=CN(N=C2)C(C)OP(O)(O)=O)C(=N1)C1=NC(F)=CC=C1F

References

General References
Not Available
Not Available

Clinical Trials

Clinical Trials
Clinical Trial & Rare Diseases Add-on Data Package
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PhaseStatusPurposeConditionsCountStart DateWhy Stopped100+ additional columns
1, 2RecruitingTreatmentLow Risk Myelodysplastic Syndromes1somestatusstop reasonjust information to hide

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available
Chromatographic Properties
Collision Cross Sections (CCS)
Not Available

Drug created at July 04, 2024 18:12 / Updated at July 08, 2024 11:33