Acorafloxacin

DB19496ExperimentalSmall molecule

Acorafloxacin is a small molecule drug. The usage of the INN stem '-oxacin' in the name indicates that Acorafloxacin is a nalidixic acid derivative antibacterial. Acorafloxacin has a monoisotopic molecular...

Mechanism: Pharmacologically active on DNA gyrase subunit B, DNA topoisomerase 4 subunit A, and DNA gyrase subunit A
Curator reviewed
Formula / weight: C₂₁H₂₃F₂N₃O₄ · 419.429 g/mol (avg)
Code names: JNJ-32729463-AAA · JNJ-Q2

Resolves to

Compound

UNII070SV15RJACAS878592-87-1ChEMBLCHEMBL1257096ChEBI229847PubChem11546234

Structure

InChIKeyVMKVDAAFMQKZJS-LFIBNONCSA-NSMILESCOC1=C2N(C=C(C(O)=O)C(=O)C2=CC(F)=C1N1CCC\C(C1)=C(/F)CN)C1CC1

Targets

P0A0K8gyrBP0C1U9parCP20831gyrAQ12809KCNH2

What you can answer from here — as of September 23, 2026

4Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

4+ReferencesStructured and connected to the statements they support

Which drugs share a target with Acorafloxacin, and which of those have an active Phase 3 trial?

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