Clamikalant

DB20383ExperimentalSmall molecule

Clamikalant is a small molecule drug. The usage of the INN stem '-kalant' in the name indicates that Clamikalant is a potassium channel blocker. Clamikalant has a monoisotopic molecular weight...

Mechanism: Pharmacologically active on ATP-binding cassette sub-family C member 9, ATP-sensitive inward rectifier potassium channel 11, and ATP-sensitive potassium channel
Curator reviewed
Formula / weight: C₁₉H₂₂ClN₃O₅S₂ · 471.97 g/mol (avg)
Code names: HMR-1883

Resolves to

Compound

UNII94301K998RCAS158751-64-5ChEMBLCHEMBL12531

Structure

InChIKeyVXTKXGKPBOLHRY-UHFFFAOYSA-NSMILESCNC(=S)NS(=O)(=O)C1=C(OC)C=CC(CCNC(=O)C2=C(OC)C=CC(Cl)=C2)=C1

Targets

O60706ABCC9Q14654KCNJ11Q15842KCNJ8

Transporters

Q09428ABCC8

What you can answer from here — as of September 13, 2026

4Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

1TransporterSubstrate / inhibitor direction, not just membership

Listed above

11+ReferencesStructured and connected to the statements they support

Which drugs share a target with Clamikalant, and which of those have an active Phase 3 trial?

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