Lysuride maleateProduct ingredient for Lisuride
- Name
- Lysuride maleate
- Drug Entry
- Lisuride
An ergot derivative that acts as an agonist at dopamine D2 receptors (dopamine agonists). It may also act as an antagonist at dopamine D1 receptors, and as an agonist at some serotonin receptors (serotonin agonists).
- Accession Number
- DBSALT001034
- Structure
- Synonyms
- Not Available
- UNII
- UV1635N8XW
- CAS Number
- 19875-60-6
- Weight
- Average: 454.527
Monoisotopic: 454.221620082 - Chemical Formula
- C24H30N4O5
- InChI Key
- CVQFAMQDTWVJSV-BAXNFHPCSA-N
- InChI
- InChI=1S/C20H26N4O.C4H4O4/c1-4-24(5-2)20(25)22-14-10-16-15-7-6-8-17-19(15)13(11-21-17)9-18(16)23(3)12-14;5-3(6)1-2-4(7)8/h6-8,10-11,14,18,21H,4-5,9,12H2,1-3H3,(H,22,25);1-2H,(H,5,6)(H,7,8)/b;2-1-/t14-,18+;/m0./s1
- IUPAC Name
- (2Z)-but-2-enedioic acid; 3,3-diethyl-1-[(4S,7R)-6-methyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1(16),2,9,12,14-pentaen-4-yl]urea
- SMILES
- OC(=O)\C=C/C(O)=O.CCN(CC)C(=O)N[C@@H]1CN(C)[C@@H]2CC3=CNC4=CC=CC(=C34)C2=C1
- External Links
- ChemSpider
- 4445576
- ChEBI
- 31776
- ChEMBL
- CHEMBL1257128
- Predicted Properties
Property Value Source Water Solubility 0.14 mg/mL ALOGPS logP 2.37 ALOGPS logP 2.17 Chemaxon logS -3.4 ALOGPS pKa (Strongest Acidic) 15.36 Chemaxon pKa (Strongest Basic) 6.88 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 2 Chemaxon Hydrogen Donor Count 2 Chemaxon Polar Surface Area 51.37 Å2 Chemaxon Rotatable Bond Count 5 Chemaxon Refractivity 101.81 m3·mol-1 Chemaxon Polarizability 38.81 Å3 Chemaxon Number of Rings 4 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon