Sulfadiazine sodiumProduct ingredient for Sulfadiazine
- Name
- Sulfadiazine sodium
- Drug Entry
- Sulfadiazine
One of the short-acting sulfonamides used in combination with pyrimethamine to treat toxoplasmosis in patients with acquired immunodeficiency syndrome and in newborns with congenital infections.
- Accession Number
- DBSALT001400
- Structure
- Synonyms
- Not Available
- UNII
- 84CS1P306F
- CAS Number
- 547-32-0
- Weight
- Average: 272.26
Monoisotopic: 272.034391 - Chemical Formula
- C10H9N4NaO2S
- InChI Key
- JLDCNMJPBBKAHH-UHFFFAOYSA-N
- InChI
- InChI=1S/C10H9N4O2S.Na/c11-8-2-4-9(5-3-8)17(15,16)14-10-12-6-1-7-13-10;/h1-7H,11H2;/q-1;+1
- IUPAC Name
- sodium 4-{[(pyrimidin-2-yl)azanidyl]sulfonyl}aniline
- SMILES
- [Na+].NC1=CC=C(C=C1)S(=O)(=O)[N-]C1=NC=CC=N1
- External Links
- ChemSpider
- 10565
- ChEMBL
- CHEMBL1200351
- Wikipedia
- Sulfadiazine
- Predicted Properties
Property Value Source Water Solubility 4.12 mg/mL ALOGPS logP 0.52 ALOGPS logP 0.39 Chemaxon logS -1.8 ALOGPS pKa (Strongest Acidic) 6.99 Chemaxon pKa (Strongest Basic) 2.01 Chemaxon Physiological Charge -1 Chemaxon Hydrogen Acceptor Count 6 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 95.17 Å2 Chemaxon Rotatable Bond Count 2 Chemaxon Refractivity 63.4 m3·mol-1 Chemaxon Polarizability 22.87 Å3 Chemaxon Number of Rings 2 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon