Doconexent sodiumProduct ingredient for Doconexent
- Name
- Doconexent sodium
- Drug Entry
- Doconexent
A mixture of fish oil and primrose oil, doconexent is used as a high-docosahexaenoic acid (DHA) supplement. DHA is a 22 carbon chain with 6 cis double bonds with anti-inflammatory effects. It can be biosythesized from alpha-linolenic acid or commercially manufactured from microalgae. It is an omega-3 fatty acid and primary structural component of the human brain, cerebral cortex, skin, and retina thus plays an important role in their development and function. The amino-phospholipid DHA is found at a high concentration across several brain subcellular fractions, including nerve terminals, microsomes, synaptic vesicles, and synaptosomal plasma membranes 10.
- Accession Number
- DBSALT002309
- Structure
Structure for Doconexent sodium (DBSALT002309)
- Synonyms
- Not Available
- UNII
- 295P7EPT4C
- CAS Number
- 81926-93-4
- Weight
- Average: 350.478
Monoisotopic: 350.22217452 - Chemical Formula
- C22H31NaO2
- InChI Key
- SNNDEWVSGZRIFE-FPYKSTABSA-M
- InChI
- InChI=1S/C22H32O2.Na/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22(23)24;/h3-4,6-7,9-10,12-13,15-16,18-19H,2,5,8,11,14,17,20-21H2,1H3,(H,23,24);/q;+1/p-1/b4-3-,7-6-,10-9-,13-12-,16-15-,19-18-;
- IUPAC Name
- sodium (4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenoate
- SMILES
- [Na+].CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCC([O-])=O
- External Links
- ChemSpider
- 28296033
- Predicted Properties
Property Value Source Water Solubility 0.000151 mg/mL ALOGPS logP 6.78 ALOGPS logP 6.75 Chemaxon logS -6.4 ALOGPS pKa (Strongest Acidic) 4.89 Chemaxon Physiological Charge -1 Chemaxon Hydrogen Acceptor Count 2 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 40.13 Å2 Chemaxon Rotatable Bond Count 14 Chemaxon Refractivity 122.23 m3·mol-1 Chemaxon Polarizability 38.35 Å3 Chemaxon Number of Rings 0 Chemaxon Bioavailability 0 Chemaxon Rule of Five No Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon