Phenacetin

DB03783ApprovedWithdrawnSmall molecule

Phenacetin was withdrawn from the Canadian market in June 1973 due to concerns regarding nephropathy (damage to or disease of the kidney).

Chemical structure of Phenacetin
Mechanism
Curator reviewed
Primary indication
Used principally as an analgesic.Curator reviewed
Formula / weight
C10H13NO2 · 179.2157 g/mol (avg)
Also known as
Acetophenetidin · Acetophenetidine · Acetophenetin · Acetphenetidin
Code names
NSC-7651

Resolves to

Compound
UNIIER0CTH01H9CAS62-44-2ChEMBLCHEMBL16073ChEBI8050PubChem4754KEGGD00569
Clinical / RWD
RxNorm8113ATCN02BE03ATCN02BE53ATCN02BE73PharmGKBPA450897
Structure
InChIKeyCPJSUEIXXCENMM-UHFFFAOYSA-NSMILESCCOC1=CC=C(NC(C)=O)C=C1
Targets
P23219PTGS1P20839IMPDH1
Transporters
Q4U2R8SLC22A6

What you can answer from here — as of September 23, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action
Listed above
1TransporterSubstrate / inhibitor direction, not just membership
Listed above
807Drug interactionsStructured to mechanism, not free text
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1Clinical trialPhase, status and sponsor resolved per trial
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3ATC codesIncluding every combination product, plus 22 drug categories
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28+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Phenacetin, and which of those have an active Phase 3 trial?

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