Fissure;Anal

Also known as: Anal Fissures / Anal Fissure / Anal fissure, unspecified / Tear of anus, nontraumatic / Fissure in ano / Fissure anal / Anal fistula (disorder) [Ambiguous] / Anal fissure (disorder)

DrugDrug NameDrug Description
DB13909Bismuth subgallateA medication used to deodorize flatulence and stools as well as hemostasis in soft tissue surgery.
DB13346BufexamacAn NSAID used to treat skin conditions like atopic eczema and inflammatory dermatoses.
DB15886CarvaseptA medication used to treat hemorrhoids, anal fissures, and pruritus ani.
DB00343DiltiazemA calcium channel blocker used to treat hypertension and to manage chronic stable angina.
DB13155EsculinAs medication, esculin is sometimes used as a vasoprotective agent. Esculin is also used in a microbiology laboratory to aid in the identification of bacterial species (especially Enterococci and Listeria),...
DB00591Fluocinolone acetonideA corticosteroid used to treat skin conditions, eczematous otitis externa, diabetic macular edema, and non-infectious uveitis of the posterior segment of the eye.
DB15821Fluocortolone caproateA corticosteroid indicated in the treatment of hemorrhoids, anal fissures, and corticosteroid-responsive dermatoses.
DB00741HydrocortisoneA glucocorticoid used to treat corticosteroid-responsive dermatoses, endocrine disorders, immune conditions, and allergic disorders.
DB14539Hydrocortisone acetateA corticosteroid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses and ulcerative colitis.
DB11341IchthammolIchthammol is also referred to as ammonium bituminosulfonate or ammonium bituminosulphonate. It is an ammonium salt of dark sulfonated shale oil (bituminous schists) produced via distillation of the oil followed...
DB00281LidocaineA local anesthetic used in a wide variety of superficial and invasive procedures.
DB01115NifedipineA dihydropyridine calcium channel blocker indicated for the management of several subtypes of angina pectoris, and hypertension.
DB12532OxetacaineAn antacid used to treat gastritis, peptic ulcer disease, heartburn, esophagitis, hiatus hernia, and anorexia.
DB09268Picosulfuric acidA stimulant laxative used for cleansing of the colon as a preparation for colonoscopy in adults.
DB00860PrednisoloneA glucocorticoid used to treat adrenocortical insufficiency, inflammatory conditions, and some cancers.
DrugDrug NameTargetType
DB13909Bismuth subgallateSerum albumincarrier
DB13346BufexamacProstaglandin G/H synthase 1target
DB13346BufexamacProstaglandin G/H synthase 2target
DB13346BufexamacHistone deacetylase 6target
DB13346BufexamacHistone deacetylase 10target
DB00343DiltiazemVoltage-dependent calcium channel gamma-1 subunittarget
DB00343DiltiazemCytochrome P450 3A4enzyme
DB00343DiltiazemCytochrome P450 2C19enzyme
DB00343DiltiazemCytochrome P450 2D6enzyme
DB00343DiltiazemCytochrome P450 3A5enzyme
DB00343DiltiazemCytochrome P450 3A7enzyme
DB00343DiltiazemP-glycoprotein 1transporter
DB00343DiltiazemCytochrome P450 2C8enzyme
DB00343DiltiazemSerum albumincarrier
DB00343DiltiazemAlpha-1-acid glycoprotein 1carrier
DB00343DiltiazemVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB13155EsculinGlutaminase kidney isoform, mitochondrialenzyme
DB13155EsculinAndrogen receptortarget
DB00591Fluocinolone acetonideCorticosteroid-binding globulincarrier
DB00591Fluocinolone acetonideGlucocorticoid receptortarget
DB00591Fluocinolone acetonideCytochrome P450 3A4enzyme
DB00591Fluocinolone acetonideAnnexin A1target
DB00591Fluocinolone acetonideAnnexin A2target
DB00591Fluocinolone acetonideAnnexin A3target
DB00591Fluocinolone acetonideAnnexin A4target
DB00591Fluocinolone acetonideAnnexin A5target
DB00741HydrocortisoneAnnexin A1target
DB00741HydrocortisoneGlucocorticoid receptortarget
DB00741HydrocortisoneSex hormone-binding globulincarrier
DB00741HydrocortisoneCytochrome P450 3A4enzyme
DB00741HydrocortisoneCytochrome P450 3A5enzyme
DB00741HydrocortisoneCytochrome P450 3A7enzyme
DB00741HydrocortisoneP-glycoprotein 1transporter
DB00741HydrocortisoneSolute carrier organic anion transporter family member 1A2transporter
DB00741HydrocortisoneCytochrome P450 11B1, mitochondrialenzyme
DB00741HydrocortisoneCytochrome P450 11B2, mitochondrialenzyme
DB00741HydrocortisoneCytochrome P450 2C8enzyme
DB00741HydrocortisoneCorticosteroid-binding globulincarrier
DB00741HydrocortisoneSolute carrier family 22 member 8transporter
DB00741Hydrocortisone3-oxo-5-beta-steroid 4-dehydrogenaseenzyme
DB00741Hydrocortisone3-oxo-5-alpha-steroid 4-dehydrogenase 2enzyme
DB00741HydrocortisoneCorticosteroid 11-beta-dehydrogenase isozyme 2enzyme
DB00741HydrocortisoneCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
DB00741HydrocortisoneCytochrome P450 2A6enzyme
DB00741HydrocortisoneCytochrome P450 1B1enzyme
DB00741HydrocortisoneCytochrome P450 2B6enzyme
DB00741HydrocortisoneCytochrome P450 2C9enzyme
DB00741HydrocortisoneCytochrome P450 2C19enzyme
DB14539Hydrocortisone acetateAnnexin A1target
DB14539Hydrocortisone acetateGlucocorticoid receptortarget
DB14539Hydrocortisone acetateSex hormone-binding globulincarrier
DB14539Hydrocortisone acetateCytochrome P450 3A4enzyme
DB14539Hydrocortisone acetateCytochrome P450 3A5enzyme
DB14539Hydrocortisone acetateCytochrome P450 3A7enzyme
DB14539Hydrocortisone acetateP-glycoprotein 1transporter
DB14539Hydrocortisone acetateSolute carrier organic anion transporter family member 1A2transporter
DB14539Hydrocortisone acetateATP-binding cassette sub-family G member 2transporter
DB14539Hydrocortisone acetateCytochrome P450 11B1, mitochondrialenzyme
DB14539Hydrocortisone acetateCytochrome P450 11B2, mitochondrialenzyme
DB14539Hydrocortisone acetateCytochrome P450 2C8enzyme
DB14539Hydrocortisone acetateCorticosteroid-binding globulincarrier
DB14539Hydrocortisone acetateCorticosteroid 11-beta-dehydrogenase isozyme 2target
DB14539Hydrocortisone acetate3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1target
DB14539Hydrocortisone acetateSolute carrier family 22 member 8transporter
DB00281LidocaineSodium channel protein type 5 subunit alphatarget
DB00281LidocaineSodium channel protein type 10 subunit alphatarget
DB00281LidocaineEpidermal growth factor receptortarget
DB00281LidocaineSodium channel protein type 9 subunit alphatarget
DB00281LidocaineCytochrome P450 1A2enzyme
DB00281LidocaineCytochrome P450 2D6enzyme
DB00281LidocaineCytochrome P450 3A4enzyme
DB00281LidocaineCytochrome P450 3A5enzyme
DB00281LidocaineCytochrome P450 3A7enzyme
DB00281LidocaineSolute carrier family 22 member 5transporter
DB00281LidocaineP-glycoprotein 1transporter
DB00281LidocaineCytochrome P450 2A6enzyme
DB00281LidocaineCytochrome P450 2B6enzyme
DB00281LidocaineCytochrome P450 2C8enzyme
DB00281LidocaineCytochrome P450 2C9enzyme
DB00281LidocaineSodium channel protein type 4 subunit alphatarget
DB00281LidocaineAlpha-1-acid glycoprotein 1target
DB00281LidocaineAlpha-1-acid glycoprotein 2target
DB01115NifedipineCytochrome P450 3A4enzyme
DB01115NifedipineCytochrome P450 2E1enzyme
DB01115NifedipineCytochrome P450 2D6enzyme
DB01115NifedipineCalmodulintarget
DB01115NifedipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB01115NifedipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB01115NifedipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB01115NifedipineVoltage-dependent L-type calcium channel subunit beta-2target
DB01115NifedipinePotassium voltage-gated channel subfamily D member 3target
DB01115NifedipineVoltage-dependent T-type calcium channeltarget
DB01115NifedipineCytochrome P450 1A2enzyme
DB01115NifedipineCytochrome P450 2A6enzyme
DB01115NifedipineCytochrome P450 2C8enzyme
DB01115NifedipineCanalicular multispecific organic anion transporter 2transporter
DB01115NifedipineP-glycoprotein 1transporter
DB01115NifedipineCanalicular multispecific organic anion transporter 1transporter
DB01115NifedipineCytochrome P450 1A1enzyme
DB01115NifedipineCytochrome P450 2B6enzyme
DB01115NifedipineNuclear receptor subfamily 1 group I member 2target
DB01115NifedipineSolute carrier organic anion transporter family member 1B1transporter
DB01115NifedipineBile salt export pumptransporter
DB01115NifedipineCytochrome P450 2C9enzyme
DB01115NifedipineSerum albumincarrier
DB01115Nifedipinealpha1-acid glycoproteincarrier
DB01115NifedipineCytochrome P450 3A5enzyme
DB12532OxetacaineCytochrome P450 3A4enzyme
DB12532OxetacaineGastrintarget
DB09268Picosulfuric acidArylsulfate sulfotransferaseenzyme
DB00860PrednisoloneCorticosteroid-binding globulincarrier
DB00860PrednisoloneCytochrome P450 3A4enzyme
DB00860PrednisoloneGlucocorticoid receptortarget
DB00860PrednisoloneSolute carrier organic anion transporter family member 1A2transporter
DB00860PrednisoloneP-glycoprotein 1transporter
DB00860PrednisoloneSerum albumincarrier
DrugDrug NamePhaseStatusCount
DB01020Isosorbide mononitrate1Withdrawn1
DB01115Nifedipine1 / 2Terminated1
DB00083Botulinum toxin type A2Completed1
DB00343Diltiazem2Recruiting1
DB00586Diclofenac4Completed1
DB00581Lactulose4Terminated1
DB00281Lidocaine4Completed1
DB00727Nitroglycerin4Withdrawn1
DB00916MetronidazoleNot AvailableCompleted1
DB00350MinoxidilNot AvailableCompleted1
DB00727NitroglycerinNot AvailableCompleted1