Pharmaco-transcriptomicsUp/down regulation of genes due to the metabolism of pharmaceutical compounds

Pharmaco-genomics Pharmaco-metabolomics Pharmaco-transcriptomics Pharmaco-proteomics Search

Displaying entries 34926 - 34950 of 102031 in total

Drug	Drug Groups	Gene	Gene ID	Change	Interaction	Chromosome	References
							Clear
3,3'-diindolylmethane	Investigational	CYP1B1	1545	upregulated	diindolylmethane results in increased expression of CYP1B1 mRNA	2p22.2	A22375
3,3'-diindolylmethane	Investigational	CYP3A4	1576	upregulated	[diindolylmethane results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA	7q22.1	A22374
3,3'-diindolylmethane	Investigational	CYP3A4	1576	upregulated	diindolylmethane results in increased expression of CYP3A4 mRNA	7q22.1	A22374
Diltiazem	Approved Investigational	IL12A	3592	downregulated	Diltiazem results in decreased expression of IL12A mRNA	3q25.33	A22377
Diltiazem	Approved Investigational	IL12B	3593	downregulated	Diltiazem results in decreased expression of IL12B mRNA	5q33.3	A22377
N,N-dimethylformamide	Experimental	LTF	4057	upregulated	Dimethylformamide results in increased expression of LTF mRNA	3p21.31	A22378
N,N-dimethylformamide	Experimental	MPO	4353	upregulated	Dimethylformamide results in increased expression of MPO mRNA	17q22	A22378
N,N-dimethylformamide	Experimental	NCF1	653361	upregulated	Dimethylformamide results in increased expression of NCF1 mRNA	7q11.23	A22378
N,N-dimethylformamide	Experimental	TNFSF10	8743	upregulated	Dimethylformamide results in increased expression of TNFSF10 mRNA	3q26	A22378
Dimethyl fumarate	Approved Investigational	CCL2	6347	downregulated	Dimethyl Fumarate results in decreased expression of CCL2 mRNA	17q12	A20261
Dimethyl fumarate	Approved Investigational	HMOX1	3162	upregulated	Dimethyl Fumarate results in increased expression of HMOX1 mRNA	22q12.3	A20261
Dimethyl fumarate	Approved Investigational	ICAM1	3383	downregulated	Dimethyl Fumarate results in decreased expression of ICAM1 mRNA	19p13.2	A20261
Dimethyl fumarate	Approved Investigational	TNF	7124	downregulated	Dimethyl Fumarate results in decreased expression of TNF mRNA	6p21.33	A20261
Dimethyl sulfoxide	Approved Investigational Vet Approved	ACTC1	70	downregulated	Dimethyl Sulfoxide results in decreased expression of ACTC1 mRNA	15q14	A22379
Dimethyl sulfoxide	Approved Investigational Vet Approved	ACTC1	70	upregulated	Dimethyl Sulfoxide results in increased expression of ACTC1 mRNA	15q14	A22379
Dimethyl sulfoxide	Approved Investigational Vet Approved	ALB	213	downregulated	Dimethyl Sulfoxide results in decreased expression of ALB mRNA	4q13.3	A22379
Dimethyl sulfoxide	Approved Investigational Vet Approved	APOA1	335	upregulated	Dimethyl Sulfoxide results in increased expression of APOA1 mRNA	11q23.3	A20610
Dimethyl sulfoxide	Approved Investigational Vet Approved	BAX	581	upregulated	Dimethyl Sulfoxide results in increased expression of BAX mRNA	19q13.33	A22380
Dimethyl sulfoxide	Approved Investigational Vet Approved	CLDN6	9074	upregulated	Dimethyl Sulfoxide results in increased expression of CLDN6 mRNA	16p13.3	A20995
Dimethyl sulfoxide	Approved Investigational Vet Approved	CLDN8	9073	upregulated	Dimethyl Sulfoxide results in increased expression of CLDN8 mRNA	21q22.11	A20995
Dimethyl sulfoxide	Approved Investigational Vet Approved	CLDN9	9080	upregulated	Dimethyl Sulfoxide results in increased expression of CLDN9 mRNA	16p13.3	A20995
Dimethyl sulfoxide	Approved Investigational Vet Approved	CSF1R	1436	upregulated	Dimethyl Sulfoxide results in increased expression of CSF1R mRNA	5q32	A22381
Dimethyl sulfoxide	Approved Investigational Vet Approved	CXCL8	3576	downregulated	Dimethyl Sulfoxide results in decreased expression of CXCL8 mRNA	4q13.3	A22382
Dimethyl sulfoxide	Approved Investigational Vet Approved	CXCL8	3576	upregulated	Dimethyl Sulfoxide results in increased expression of CXCL8 mRNA	4q13.3	A21428
Dimethyl sulfoxide	Approved Investigational Vet Approved	EDN2	1907	downregulated	Dimethyl Sulfoxide results in decreased expression of EDN2 mRNA	1p34.2	A22383

Displaying entries 34926 - 34950 of 102031 in total

Pharmaco-transcriptomicsUp/down regulation of genes due to the metabolism of pharmaceutical compounds

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