Annexin A4
Details
- Name
- Annexin A4
- Synonyms
- 35-beta calcimedin
- Annexin IV
- Annexin-4
- ANX4
- Carbohydrate-binding protein p33/p41
- Chromobindin-4
- Endonexin I
- Lipocortin IV
- P32.5
- PAP-II
- Placental anticoagulant protein II
- PP4-X
- Protein II
- Gene Name
- ANXA4
- Organism
- Humans
- Amino acid sequence
>lcl|BSEQ0049654|Annexin A4 MATKGGTVKAASGFNAMEDAQTLRKAMKGLGTDEDAIISVLAYRNTAQRQEIRTAYKSTI GRDLIDDLKSELSGNFEQVIVGMMTPTVLYDVQELRRAMKGAGTDEGCLIEILASRTPEE IRRISQTYQQQYGRSLEDDIRSDTSFMFQRVLVSLSAGGRDEGNYLDDALVRQDAQDLYE AGEKKWGTDEVKFLTVLCSRNRNHLLHVFDEYKRISQKDIEQSIKSETSGSFEDALLAIV KCMRNKSAYFAEKLYKSMKGLGTDDNTLIRVMVSRAEIDMLDIRAHFKRLYGKSLYSFIK GDTSGDYRKVLLVLCGGDD
- Number of residues
- 319
- Molecular Weight
- 35882.36
- Theoretical pI
- Not Available
- GO Classification
- Functionscalcium ion binding / calcium-dependent phospholipid binding / calcium-dependent protein binding / identical protein binding / NF-kappaB binding / phospholipase inhibitor activityProcessesepithelial cell differentiation / negative regulation of apoptotic process / negative regulation of interleukin-8 secretion / negative regulation of NF-kappaB transcription factor activity / Notch signaling pathway / regulation of transcription from RNA polymerase II promoter / signal transductionComponentscell surface / cytoplasm / extracellular exosome / nuclear membrane / nucleus / perinuclear region of cytoplasm / plasma membrane / vesicle membrane
- General Function
- Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis.
- Specific Function
- Calcium ion binding
- Pfam Domain Function
- Annexin (PF00191)
- Transmembrane Regions
- Not Available
- Cellular Location
- Not Available
- Gene sequence
>lcl|BSEQ0049655|Annexin A4 (ANXA4) ATGGCCATGGCAACCAAAGGAGGTACTGTCAAAGCTGCTTCAGGATTCAATGCCATGGAA GATGCCCAGACCCTGAGGAAGGCCATGAAAGGGCTCGGCACCGATGAAGACGCCATTATT AGCGTCCTTGCCTACCGCAACACCGCCCAGCGCCAGGAGATCAGGACAGCCTACAAGAGC ACCATCGGCAGGGACTTGATAGACGACCTGAAGTCAGAACTGAGTGGCAACTTCGAGCAG GTGATTGTGGGGATGATGACGCCCACGGTGCTGTATGACGTGCAAGAGCTGCGAAGGGCC ATGAAGGGAGCCGGCACTGATGAGGGCTGCCTAATTGAGATCCTGGCCTCCCGGACCCCT GAGGAGATCCGGCGCATAAGCCAAACCTACCAGCAGCAATATGGACGGAGCCTTGAAGAT GACATTCGCTCTGACACATCGTTCATGTTCCAGCGAGTGCTGGTGTCTCTGTCAGCTGGT GGGAGGGATGAAGGAAATTATCTGGACGATGCTCTCGTGAGACAGGATGCCCAGGACCTG TATGAGGCTGGAGAGAAGAAATGGGGGACAGATGAGGTGAAATTTCTAACTGTTCTCTGT TCCCGGAACCGAAATCACCTGTTGCATGTGTTTGATGAATACAAAAGGATATCACAGAAG GATATTGAACAGAGTATTAAATCTGAAACATCTGGTAGCTTTGAAGATGCTCTGCTGGCT ATAGTAAAGTGCATGAGGAACAAATCTGCATATTTTGCTGAAAAGCTCTATAAATCGATG AAGGGCTTGGGCACCGATGATAACACCCTCATCAGAGTGATGGTTTCTCGAGCAGAAATT GACATGTTGGATATCCGGGCACACTTCAAGAGACTCTATGGAAAGTCTCTGTACTCGTTC ATCAAGGGTGACACATCTGGAGACTACAGGAAAGTACTGCTTGTTCTCTGTGGAGGAGAT GATTAA
- Chromosome Location
- 2
- Locus
- 2p13.3
- External Identifiers
Resource Link UniProtKB ID P09525 UniProtKB Entry Name ANXA4_HUMAN HGNC ID HGNC:542 - General References
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