Solute carrier family 41 member 1
Details
- Name
- Solute carrier family 41 member 1
- Synonyms
- Not Available
- Gene Name
- SLC41A1
- Organism
- Humans
- Amino acid sequence
>lcl|BSEQ0052296|Solute carrier family 41 member 1 MSSKPEPKDVHQLNGTGPSASPCSSDGPGREPLAGTSEFLGPDGAGVEVVIESRANAKGV REEDALLENGSQSNESDDVSTDRGPAPPSPLKETSFSIGLQVLFPFLLAGFGTVAAGMVL DIVQHWEVFQKVTEVFILVPALLGLKGNLEMTLASRLSTAANIGHMDTPKELWRMITGNM ALIQVQATVVGFLASIAAVVFGWIPDGHFSIPHAFLLCASSVATAFIASLVLGMIMIGVI IGSRKIGINPDNVATPIAASLGDLITLALLSGISWGLYLELNHWRYIYPLVCAFFVALLP VWVVLARRSPATREVLYSGWEPVIIAMAISSVGGLILDKTVSDPNFAGMAVFTPVINGVG GNLVAVQASRISTFLHMNGMPGENSEQAPRRCPSPCTTFFSPDVNSRSARVLFLLVVPGH LVFLYTISCMQGGHTTLTLIFIIFYMTAALLQVLILLYIADWMVHWMWGRGLDPDNFSIP YLTALGDLLGTGLLALSFHVLWLIGDRDTDVGD
- Number of residues
- 513
- Molecular Weight
- 54900.26
- Theoretical pI
- Not Available
- GO Classification
- Functionsdivalent inorganic cation transmembrane transporter activity / magnesium / magnesium ion transmembrane transporter activity / transmembrane transporter activityProcessescellular magnesium ion homeostasis / cellular response to magnesium ion / divalent metal ion transport / magnesium ion transmembrane transport / magnesium ion transportComponentsbasolateral plasma membrane / cell / integral component of membrane / plasma membrane / protein-containing complex
- General Function
- Acts as a magnesium transporter that is responsive to magnesium balance.
- Specific Function
- Divalent inorganic cation transmembrane transporter activity
- Pfam Domain Function
- MgtE (PF01769)
- Transmembrane Regions
- 102-122 185-205 222-242 257-277 286-306 316-336 346-366 411-431 439-459 484-504
- Cellular Location
- Cell membrane
- Gene sequence
>lcl|BSEQ0052297|Solute carrier family 41 member 1 (SLC41A1) ATGTCCTCTAAGCCAGAGCCGAAGGACGTCCACCAACTGAACGGGACTGGCCCTTCTGCC TCTCCCTGCTCTTCAGATGGCCCAGGGAGAGAGCCCTTGGCTGGGACCTCAGAGTTCCTG GGGCCTGATGGGGCTGGGGTAGAGGTGGTGATTGAGTCTCGGGCCAACGCCAAGGGGGTT CGGGAGGAGGACGCCCTGCTGGAGAACGGGAGCCAGAGCAACGAAAGTGACGACGTCAGC ACAGACCGTGGCCCTGCGCCACCTTCCCCGCTCAAGGAGACCTCCTTTTCCATCGGGCTG CAAGTACTGTTTCCATTCCTCCTGGCAGGCTTTGGGACCGTGGCTGCTGGCATGGTGTTG GACATCGTGCAGCACTGGGAAGTCTTCCAGAAGGTGACAGAGGTCTTCATCCTAGTGCCT GCGCTGCTGGGGCTCAAAGGGAACCTGGAAATGACCCTGGCATCAAGGCTTTCCACTGCA GCCAACATTGGACACATGGACACACCCAAGGAGCTCTGGCGGATGATCACTGGGAACATG GCCCTCATCCAGGTGCAGGCCACGGTGGTGGGCTTCCTGGCGTCCATCGCAGCCGTCGTC TTTGGCTGGATCCCTGATGGCCACTTCAGTATTCCGCACGCCTTCCTGCTCTGTGCTAGC AGCGTGGCCACAGCCTTCATTGCCTCCCTGGTACTGGGTATGATCATGATTGGAGTCATC ATTGGCTCTCGCAAGATTGGGATCAACCCAGACAACGTGGCCACACCCATTGCTGCCAGC CTGGGCGACCTCATCACCTTGGCGCTGCTCTCAGGCATCAGCTGGGGACTCTACCTGGAA CTGAATCACTGGCGATACATCTACCCACTGGTGTGTGCTTTCTTTGTGGCCCTGCTGCCT GTCTGGGTGGTGCTGGCCCGACGAAGTCCAGCCACAAGGGAGGTGTTGTACTCGGGCTGG GAGCCTGTTATCATTGCCATGGCCATCAGCAGTGTGGGAGGCCTCATCTTGGACAAGACT GTCTCAGACCCCAACTTTGCTGGGATGGCTGTCTTCACGCCTGTGATTAATGGTGTTGGG GGCAATCTGGTGGCAGTGCAGGCCAGCCGCATCTCCACCTTCCTGCACATGAATGGAATG CCCGGAGAGAACTCTGAGCAAGCTCCTCGCCGCTGTCCCAGTCCTTGTACCACCTTCTTC AGCCCTGATGTGAATTCTCGCTCAGCCCGGGTCCTCTTCCTCCTCGTGGTCCCAGGACAC CTGGTGTTCCTCTACACCATCAGCTGTATGCAGGGCGGGCACACCACCCTCACACTCATC TTCATCATCTTCTATATGACAGCTGCACTGCTCCAGGTGCTGATTCTCCTGTACATCGCA GACTGGATGGTGCACTGGATGTGGGGCCGGGGCCTGGACCCGGACAACTTCTCCATCCCA TACTTGACTGCTCTGGGGGACCTGCTTGGCACTGGGCTCCTAGCACTCAGCTTCCATGTT CTCTGGCTCATAGGGGACCGAGACACGGATGTCGGGGACTAG
- Chromosome Location
- 1
- Locus
- 1q32.1
- External Identifiers
Resource Link UniProtKB ID Q8IVJ1 UniProtKB Entry Name S41A1_HUMAN HGNC ID HGNC:19429 - General References
- Wabakken T, Rian E, Kveine M, Aasheim HC: The human solute carrier SLC41A1 belongs to a novel eukaryotic subfamily with homology to prokaryotic MgtE Mg2+ transporters. Biochem Biophys Res Commun. 2003 Jul 4;306(3):718-24. doi: 10.1016/s0006-291x(03)01030-1. [Article]
- Bechtel S, Rosenfelder H, Duda A, Schmidt CP, Ernst U, Wellenreuther R, Mehrle A, Schuster C, Bahr A, Blocker H, Heubner D, Hoerlein A, Michel G, Wedler H, Kohrer K, Ottenwalder B, Poustka A, Wiemann S, Schupp I: The full-ORF clone resource of the German cDNA Consortium. BMC Genomics. 2007 Oct 31;8:399. [Article]
- Goytain A, Quamme GA: Functional characterization of human SLC41A1, a Mg2+ transporter with similarity to prokaryotic MgtE Mg2+ transporters. Physiol Genomics. 2005 May 11;21(3):337-42. doi: 10.1152/physiolgenomics.00261.2004. Epub 2005 Feb 15. [Article]