6-phospho-beta-glucosidase BglT
Details
- Name
- 6-phospho-beta-glucosidase BglT
- Synonyms
- 3.2.1.86
- Gene Name
- bglT
- Organism
- Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
- Amino acid sequence
>lcl|BSEQ0010974|6-phospho-beta-glucosidase BglT MRIAVIGGGSSYTPELVKGLLDISEDVRIDEVIFYDIDEEKQKIVVDFVKRLVKDRFKVL ISDTFEGAVVDAKYVIFQFRPGGLKGRENDEGIPLKYGLIGQETTGVGGFSAALRAFPIV EEYVDTVRKTSNATIVNFTNPSGHITEFVRNYLEYEKFIGLCNVPINFIREIAEMFSARL EDVFLKYYGLNHLSFIEKVFVKGEDVTEKVFENLKLKLSNIPDEDFPTWFYDSVRLIVNP YLRYYLMEKKMFKKISTHELRAREVMKIEKELFEKYRTAVEIPEELTKRGGSMYSTAAAH LIRDLETDEGKIHIVNTRNNGSIENLPDDYVLEIPCYVRSGRVHTLSQGKGDHFALSFIH AVKMYERLTIEAYLKRSKKLALKALLSHPLGPDVEDAKDLLEEILEANREYVKLG
- Number of residues
- 415
- Molecular Weight
- 47626.38
- Theoretical pI
- 5.92
- GO Classification
- Functions6-phospho-beta-glucosidase activity / metal ion binding / oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptorProcessescarbohydrate metabolic process
- General Function
- Oxidoreductase activity, acting on the ch-oh group of donors, nad or nadp as acceptor
- Specific Function
- Hydrolyzes cellobiose 6'-phosphate into glucose 6-phosphate (Glc6P) and glucose.
- Pfam Domain Function
- Transmembrane Regions
- Not Available
- Cellular Location
- Cytoplasmic
- Gene sequence
>lcl|BSEQ0010975|6-phospho-beta-glucosidase BglT (bglT) ATGAGAATTGCGGTGATAGGTGGGGGAAGCAGCTACACCCCGGAGCTGGTGAAGGGACTT CTCGACATTTCCGAGGATGTTCGCATCGACGAGGTGATCTTCTACGACATCGACGAAGAA AAGCAGAAAATCGTCGTTGATTTCGTGAAGAGACTCGTCAAAGACAGGTTCAAGGTGCTC ATAAGCGACACCTTCGAGGGTGCTGTCGTGGACGCGAAGTACGTGATCTTTCAGTTCAGA CCCGGCGGACTCAAAGGTAGAGAAAACGACGAAGGCATTCCGCTGAAGTACGGTCTCATA GGTCAAGAGACAACGGGGGTTGGGGGATTTTCAGCGGCTTTGAGGGCGTTTCCCATAGTA GAAGAGTACGTTGATACCGTGAGAAAAACATCGAACGCGACCATCGTAAACTTCACCAAC CCATCCGGCCACATTACGGAGTTCGTGAGAAACTACCTCGAATACGAAAAATTCATAGGT CTCTGCAACGTTCCCATAAACTTCATCCGGGAGATCGCAGAGATGTTCTCAGCAAGGCTC GAAGACGTGTTCCTGAAGTACTACGGCCTCAACCATCTGAGCTTCATAGAGAAGGTCTTC GTAAAAGGTGAAGACGTGACGGAAAAGGTTTTCGAGAACCTGAAGCTGAAGCTCTCCAAC ATACCAGACGAGGATTTCCCGACGTGGTTCTACGACTCGGTGAGACTCATTGTGAATCCT TACCTGAGGTACTACCTGATGGAGAAGAAGATGTTCAAAAAGATCTCCACACACGAGCTC AGAGCAAGGGAAGTGATGAAGATAGAGAAAGAACTCTTCGAGAAGTACAGAACCGCTGTC GAGATACCGGAGGAACTCACAAAACGCGGTGGCAGCATGTATTCCACAGCGGCAGCTCAC CTGATAAGAGACCTCGAAACCGACGAAGGAAAGATACACATCGTGAACACGAGAAACAAC GGCTCGATCGAGAACCTCCCGGATGATTACGTTCTGGAGATCCCGTGTTATGTGAGATCC GGCAGGGTTCACACGCTCTCGCAGGGAAAAGGAGATCACTTTGCTCTTTCTTTCATCCAC GCGGTGAAGATGTACGAGCGACTCACAATAGAAGCGTATCTGAAGAGATCGAAAAAACTC GCTCTAAAGGCTTTGCTTTCCCATCCTCTCGGACCCGATGTGGAGGACGCAAAAGACCTT CTCGAAGAGATACTGGAGGCGAACAGAGAATACGTGAAACTGGGGTGA
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID Q9X108 UniProtKB Entry Name BGLT_THEMA GenBank Protein ID 4981838 GenBank Gene ID AE000512 - General References
- Nelson KE, Clayton RA, Gill SR, Gwinn ML, Dodson RJ, Haft DH, Hickey EK, Peterson JD, Nelson WC, Ketchum KA, McDonald L, Utterback TR, Malek JA, Linher KD, Garrett MM, Stewart AM, Cotton MD, Pratt MS, Phillips CA, Richardson D, Heidelberg J, Sutton GG, Fleischmann RD, Eisen JA, White O, Salzberg SL, Smith HO, Venter JC, Fraser CM: Evidence for lateral gene transfer between Archaea and bacteria from genome sequence of Thermotoga maritima. Nature. 1999 May 27;399(6734):323-9. [Article]
- Yip VL, Varrot A, Davies GJ, Rajan SS, Yang X, Thompson J, Anderson WF, Withers SG: An unusual mechanism of glycoside hydrolysis involving redox and elimination steps by a family 4 beta-glycosidase from Thermotoga maritima. J Am Chem Soc. 2004 Jul 14;126(27):8354-5. [Article]
- Varrot A, Yip VL, Li Y, Rajan SS, Yang X, Anderson WF, Thompson J, Withers SG, Davies GJ: NAD+ and metal-ion dependent hydrolysis by family 4 glycosidases: structural insight into specificity for phospho-beta-D-glucosides. J Mol Biol. 2005 Feb 18;346(2):423-35. Epub 2005 Jan 7. [Article]