Reaction: Irinotecan to 1 product
oxidationMetabolism of Irinotecan
Irinotecan is converted to NPC by Cytochrome P450 3A4 and Cytochrome P450 3A5.
- Reaction
- Direction
- Activity
- inactive
- Comments
- NPC is a weak topoisomerase I inhibitor.
What you can answer from here — as of March 25, 2024
2EnzymesEach linked to its target cardListed above
Which other drugs are metabolised by Cytochrome P450 3A4 and Cytochrome P450 3A5, and which of those pairings are clinically significant?
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