Reaction: Orantinib to 1 product

Aromatic hydroxylationMetabolism of Orantinib

Orantinib is converted to 3‐(5‐([(3Z)‐7‐hydroxy‐2‐oxo‐2,3‐dihydro‐1H‐indol‐3‐ylidene]methyl)‐2,4‐dimethyl‐1H‐pyrrol‐3‐yl)propanoic acid by Cytochrome P450 1A1, Cytochrome P450 1A2, and Cytochrome P450 2C8.

Direction

What you can answer from here — as of October 27, 2017

3EnzymesEach linked to its target card
Listed above
1ReferenceThe literature this reaction is curated from
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Which other drugs are metabolised by Cytochrome P450 1A1, Cytochrome P450 1A2, and Cytochrome P450 2C8, and which of those pairings are clinically significant?

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