Reaction: hydroxilated form of dolutegravir (M3) to 2 products
hydrolysisMetabolism of Dolutegravir
hydroxilated form of dolutegravir (M3) is converted to 2,4- difluorobenzaldehyde (M5 dolutegravir) and hydrolized form of dolutegravir (M1) by Cytochrome P450 1A1 and Cytochrome P450 1B1.
- Reaction
- Direction
- Activity
- active
What you can answer from here — as of December 09, 2017
2EnzymesEach linked to its target cardListed above
Which other drugs are metabolised by Cytochrome P450 1A1 and Cytochrome P450 1B1, and which of those pairings are clinically significant?
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