Reaction: N-(2-aminoethyl)-2-(2,6-dichlorophenoxy)propanamide to 2 products

Oxidative deaminationMetabolism of Lofexidine

N-(2-aminoethyl)-2-(2,6-dichlorophenoxy)propanamide is converted to 2,6-dichlorophenol and 2-(2,6-dichlorophenoxy) propionic acid by Cytochrome P450 2D6, Cytochrome P450 1A2, and Cytochrome P450 2C19.

Direction
Activity
active

What you can answer from here — as of May 18, 2018

3EnzymesEach linked to its target card
Listed above

Which other drugs are metabolised by Cytochrome P450 2D6, Cytochrome P450 1A2, and Cytochrome P450 2C19, and which of those pairings are clinically significant?

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