Reaction: Vitamin E to 1 product

Reaction
Vitamin E
DB00163
13'-hydroxy-alpha-tocopherol
DBMET02310
Reaction type
hydroxylation
Direction
Major circulating metabolite?
No
Spontaneous?
No
Activity
unknown
References
  1. Brigelius-Flohe R: Adverse effects of vitamin E by induction of drug metabolism. Genes Nutr. 2007 Dec;2(3):249-56. doi: 10.1007/s12263-007-0055-0. Epub 2007 Oct 16. [Article]
  2. Schmolz L, Birringer M, Lorkowski S, Wallert M: Complexity of vitamin E metabolism. World J Biol Chem. 2016 Feb 26;7(1):14-43. doi: 10.4331/wjbc.v7.i1.14. [Article]
Comments
omega hydroxylation
Enzymes
EnzymeKmVmaxRole
Cytochrome P450 3A4Not AvailableNot Availableconfirmed
Leukotriene-B(4) omega-hydroxylase 1Not AvailableNot Availableimplied