Reaction: Endoxifen (4-hydroxy-N-desmethyltamoxifen) to 1 product
glucuronidationMetabolism of Tamoxifen
Endoxifen (4-hydroxy-N-desmethyltamoxifen) is converted to Tamoxifen Glucuronides by UDP-glucuronosyltransferase 1A8, UDP-glucuronosyltransferase 1A10, UDP-glucuronosyltransferase 2B7 and 1 other enzyme.
- Reaction
- Direction
What you can answer from here — as of August 02, 2019
4EnzymesEach linked to its target cardListed above
Which other drugs are metabolised by UDP-glucuronosyltransferase 1A8, UDP-glucuronosyltransferase 1A10, and UDP-glucuronosyltransferase 2B7, and which of those pairings are clinically significant?
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