Reaction: Aprepitant to 1 product
O-dealkylationMetabolism of Aprepitant
Aprepitant is converted to (2R)-2-(4-fluorophenyl)-2-{[(5-oxo-2,5-dihydro-1H-1,2,4-triazol-3-yl)methyl]amino}acetic acid by Cytochrome P450 3A4, Cytochrome P450 1A2, and Cytochrome P450 2C19.
- Reaction
- Direction
- Not Available
What you can answer from here — as of June 18, 2012
3EnzymesEach linked to its target cardListed above
Which other drugs are metabolised by Cytochrome P450 3A4, Cytochrome P450 1A2, and Cytochrome P450 2C19, and which of those pairings are clinically significant?
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