Reaction: Febuxostat to 1 product

Reaction
Reaction type
glucuronidation
Direction
Major circulating metabolite?
Yes
Spontaneous?
No
Activity
unknown
References
  1. Grabowski BA, Khosravan R, Vernillet L, Mulford DJ: Metabolism and excretion of [14C] febuxostat, a novel nonpurine selective inhibitor of xanthine oxidase, in healthy male subjects. J Clin Pharmacol. 2011 Feb;51(2):189-201. doi: 10.1177/0091270010365549. Epub 2010 Mar 30. [Article]
  2. FDA Approved Products: ULORIC (febuxostat) tablets, for oral use (February 2019) [Link]
Comments
Not Available
Enzymes
EnzymeKmVmaxRole
UDP-glucuronosyltransferase 1-1Not AvailableNot Availableimplied
UDP-glucuronosyltransferase 1-3Not AvailableNot Availableimplied
UDP-glucuronosyltransferase 1-9Not AvailableNot Availableimplied
UDP-glucuronosyltransferase 2B7Not AvailableNot Availableimplied