Reaction: N-desmethyl enzalutamide to 1 product

Major circulating metaboliteMetabolism of Enzalutamide

N-desmethyl enzalutamide is converted to Carboxyl metabolite enzalutamide (M1) by Liver carboxylesterase 1, Cytochrome P450 3A4, and Cytochrome P450 2C8.

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What you can answer from here — as of September 21, 2022

3EnzymesEach linked to its target card
Listed above

Which other drugs are metabolised by Liver carboxylesterase 1, Cytochrome P450 3A4, and Cytochrome P450 2C8, and which of those pairings are clinically significant?

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